Naohiro Hozumi

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We have been developing a scanning acoustic microscope (SAM) system for medicine and biology featuring quantitative measurement of ultrasonic parameters of soft tissues. In the present study, we propose a new concept sound speed microscopy that can measure the thickness and speed of sound in the tissue using fast Fourier transform of a single pulsed wave(More)
The authors have proposed a new type of ultrasonic microscopy for biological tissue characterization. The system is driven by a nanosecond pulse voltage, the generated acoustic wave being reflected at the front and rear side of the sliced tissue. In this report, a time-frequency analysis was applied to determine the sound speed thorough the tissue.(More)
We have been developing a scanning acoustic microscope (SAM) system for medicine and biology featuring quantitative measurement of ultrasonic speed and attenuation of soft tissues. In the present study, we will propose a new concept ultrasonic speed microscopy that can measure the thickness and ultrasonic speed using fast Fourier transform of a single(More)
High frequency ultrasound is suitable for non-invasive evaluation of skin because it can obtain both morphological and biomechanical information. A specially developed acoustic microscope system with the central frequency of 100 MHz was developed. The system was capable of (1) conventional C-mode acoustic microscope imaging of thinly sliced tissue, (2)(More)
This paper proposes a new method for microscopic acoustic imaging that utilizes the cross sectional acoustic impedance of biological soft tissues. In the system, a focused acoustic beam with a wide band frequency of 30-100 MHz is transmitted across a plastic substrate on the rear side of which a soft tissue object is placed. By scanning the focal point(More)
A new method for two-dimensional acoustic impedance imaging for biological tissue characterization with micro-scale resolution was proposed. A biological tissue was placed on a plastic substrate with a thickness of 0.5mm. A focused acoustic pulse with a wide frequency band was irradiated from the "rear side" of the substrate. In order to generate the(More)
Regenerated skin with 3-dimensional structure is desired for the treatment of large burn and for the plastic surgery. High frequency ultrasound is suitable for non-destructive testing of the skin model because it provides information on morphology and mechanical properties. In this paper, spectral parameters of ultrasound radio-frequency signal from a(More)
Since 1985, we have been developing a scanning acoustic microscope (SAM) system for biomedical use and have been investigating the acoustic properties of various organs and disease states by using this SAM system. In biomedicine, SAM is useful for intraoperative pathological examination, study of low-frequency ultrasonic images, and assessment of(More)