Nao Ohgushi

Learn More
We examined the role of opioid receptor subtypes in the contraction and release of acetylcholine (ACh) and norepinephrine in longitudinal muscle-myenteric plexus preparations of the guinea pig ileum. [D-Ala2, N-Me-Phe4, Gly5-ol]enkephalin (DAMGO) (10(-8) to 10(-5) M) inhibited the contraction and the release of ACh evoked by 0.2 and 1 Hz of electrical(More)
When AR42J cells, an amylase-secreting pancreatic exocrine cell line, were treated with activin A, cells extended neuritelike processes, and, concomitantly, amylase-containing vesicles disappeared. Immunofluorescence and immunoelectron microscopy revealed that these processes had neurite-specific cytoskeletal architectures: neurofilaments and microtubule(More)
A case of esophageal carcinoma which showed an upper mediastinal mass shadow on plain chest X-ray film and varicoid lesions on esophagogram is reported. The findings seemed compatible with "downhill" varices, an unusual form of esophageal varices caused by superior vena caval obstruction. In this case, contrast-enhanced computed tomography (CE-CT) was(More)
The aim of this study was (1) to fabricate non-woven meshes from a biodegradable polymer, poly(γ-benzylL-glutamate), by electrospinning and subsequent hydrolysis of the ester bond on the polymer side-chain in an aqueous solution of NaOH, creating surface carboxyl groups on the fibers, and (2) to determine the effect of hydrolysis time on water wettability(More)
Oral co-administration of folic acid (pteroylglutamic acid, PteGlu) potentiates the decrease of plasma 5-methyltetrahydrofolic acid (5-CH3-H4PteGlu) concentration induced by pyrimethamine (PYR) in rats. To clarify the mechanisms of this potentiated decrease, we examined the effects of PteGlu and PYR on intestinal absorption of folates in rat jejunum loops,(More)
During the 7 years from 1980 to 1986, 2860 cases of bladder tumors were registered in the Tokai Urological Cancer Registry. Among the 2860 cases, 2304 cases were selected from the registered cases for the present study. The 5-year relative (actual) survival rates were 73.8% (61.9%) of all patients; 48.9% (42.4%) in those with malignant neoplasma of urinary(More)