Ricardo Sidharth1
Yan Wang1
Hwayoung Um1
Edie Simon1
1Ricardo Sidharth
1Yan Wang
1Hwayoung Um
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Flavonols are produced by the desaturation of dihydroflavanols, which is catalyzed by flavonol synthase (FLS). FLS belongs to the 2-oxoglutarate iron-dependent oxygenase family. The full-length cDNA and genomic DNA sequences of the FLS gene (designated as GbFLS) were isolated from Ginkgo biloba. The full-length cDNA of GbFLS contained a 1023-bp open reading(More)
The effect of leucine on glucose-stimulated insulin secretion (GSIS) in pancreatic beta-cells is quite controversial, and mechanism involved in the effect has not been elucidated yet. Consequently, we aimed to investigate effect of leucine on GSIS and its mechanism focusing on contribution of AMP-activated protein kinase (AMPK) and pancreatic/duodenal(More)
SBA-15 prepared via ethanol extraction for template removing was grafted with three kinds of amine precursors (mono-, di-, tri-aminosilanes) to synthesis new CO 2 adsorbents. The SBA-15 support and the obtained adsorbents were characterized by X-ray diffraction (XRD), small-angle X-ray scattering (SAXS), N 2 adsorption/desorption, thermogravimetry (TG),(More)
Germline and somatic mutations in key genes of the mammalian target of rapamycin (mTOR) pathway have been identified in seizure-associated disorders. mTOR mutations lead to aberrant activation of mTOR signaling, and, although affected neurons are critical for epileptogenesis, the role of mTOR activation in glial cells remains poorly understood. We(More)
ii To my grandmother, Xuerong Zhang To my parents, Xingchao Liang and Xiaoyu Wang In memory of my grandfather, Dazhang Liang iii ACKNOWLEDGMENTS I would like to thank my advisor, Professor Edward J. Delp, for his guidance and support along the way of my Ph.D study. I am very grateful to my advisor for giving me this valuable opportunity to study and(More)
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