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High dietary n-6/n-3 PUFA ratio promotes HDL cholesterol level, but does not suppress atherogenesis in apolipoprotein E-null mice 1.
AIM Dietary fatty acids affect atherogenesis, which was presumed to be partly related to HDL cholesterol (HDL-C) metabolism. The major aim of the work was to analyze various ratios of n-6/n-3 PUFAExpand
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Visualizing peroxynitrite fluxes in endothelial cells reveals the dynamic progression of brain vascular injury.
Accumulating evidence suggests that formation of peroxynitrite (ONOO(-)) in the cerebral vasculature contributes to the progression of ischemic damage, while the underlying molecular mechanismsExpand
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Serum uric acid levels in patients with amyotrophic lateral sclerosis: a meta-analysis
The pathogenic mechanism of ALS remains unclear. However, increasing evidence has indicated that uric acid (UA) may play a protective role in the pathogenesis of ALS. The aim of this study was toExpand
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Nimotuzumab Combined with Chemotherapy is a Promising Treatment for Locally Advanced and Metastatic Esophageal Cancer
Background Nimotuzumab is an anti-EGFR monoclonal antibody which has been widely used in cancer treatment. However, the safety and efficacy of nimotuzumab combined with chemotherapy in locallyExpand
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Catalytic activity of biomimetic model of cytochrome P450 in oxidation of dopamine.
The introduction of electron-withdrawing group into porphyrin molecule as cytochrome P450 model can tune the energy level and have an effect on the electronic structure. In this work, linking withExpand
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Fabrication of Novel Electrochemical Biosensor Based on Graphene Nanohybrid to Detect H2O2 Released from Living Cells with Ultrahigh Performance.
In this paper, a new class of metal-free nanocarbon catalyst-nitrogen (N) and sulfur (S) codoped graphene quantum dot/graphene (NS-GQD/G) hybrid nanosheets-was designed and synthesized for sensitiveExpand
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A novel electrochemical biomimetic sensor based on poly(Cu-AMT) with reduced graphene oxide for ultrasensitive detection of dopamine.
A polymerized film of copper-2-amino-5-mercapto-1,3,4-thiadiazole (Cu(II)-AMT) complex (poly(Cu-AMT)) was successfully achieved via a simple and low-cost electrochemical methodology. Subsequently, aExpand
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Endogenous Polysialic Acid Based Micelles for Calmodulin Antagonist Delivery against Vascular Dementia.
Clinical treatment for vascular dementia still remains a challenge mainly due to the blood-brain barrier (BBB). Here, a micelle based on polysialic acid (PSA), which is a hydrophilic and endogenousExpand
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Boosted Sensor Performance by Surface Modification of Bifunctional rht-Type Metal-Organic Framework with Nanosized Electrochemically Reduced Graphene Oxide.
The surface and interface could be designed to enhance properties of electrocatalysts, and they are regarded as the key characteristics. This report describes surface modification of a bifunctionalExpand
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Antitumor and antimetastatic effects of pemetrexed-loaded targeted nanoparticles in B16 bearing mice
Abstract Using nanoparticle delivery for anticancer therapy is a potential new drug modality. We developed a novel gelatinase–stimuli nanoparticle. In this study, we studied the antitumor andExpand
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