Nanette M Borren

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BACKGROUND Angiographic overestimation of coronary artery stenosis severity may result in unnecessary revascularization and is possibly more prevalent with increasing age. AIM To identify whether age is an independent clinical predictor for angiographic overestimation of a coronary artery stenosis. METHODS Fractional flow reserve (FFR) of 335 coronary(More)
OBJECTIVE To explore the predictors of deferred lesion failure (DLF) in patients with diabetes mellitus (DM) and lesions with a fractional flow reserve (FFR) >0.80 and to examine whether a predictive relationship between negative FFR values (>0.80-1.00) and DLF exists. BACKGROUND DM is associated with rapidly progressive atherosclerosis and predictors of(More)
An accurate diagnosis is of great importance for appropriate treatment and estimation of prognosis in patients with ischemic heart disease. The current gold standard for the diagnosis of stable coronary artery disease (CAD) is invasive coronary angiography [1]. Although its invasive nature carries a nonnegligible risk and adds significant costs [2], an(More)
Hybrid cardiac SPECT-CT is a technique in which data from both nuclear single photon emission tomography (SPECT) and a CT scan are combined. These techniques are complementary to each other, as CT provides information about anatomy of coronary arteries (stenosis, calcification, aberrant vessels) while SPECT detects functional consequences such as myocardial(More)
BACKGROUND SPECT Myocardial perfusion imaging (MPI) is associated with a relatively high radiation burden and decreasing image quality in heavy patients. Patient-specific low-activity protocols (PLAPs) are suggested but follow-up data is lacking. Our aim was to compare the use of a standard fixed-activity protocol (FAP) with a PLAP in cadmium zinc telluride(More)
OBJECTIVES This study compared the prevalence of angiographic underestimation of left anterior descending artery (LAD) lesions with non-LAD lesions. BACKGROUND Coronary angiography cannot assess the functional severity of a coronary stenosis. Previous studies suggested that lesions of the LAD are more often angiographically underestimated, but evidence is(More)
s of the 12th Congress of ECCO – European Crohn’s and Colitis Organisation S91 in the gut. However, during chronic inflammatory conditions, such as Inflammatory Bowel Disease (IBD, excessive neutrophil accumulation can lead to tissue damage, delayed tissue repair and loss of homeostasis. Thus, we aim to identify the role and function of neutrophils in the(More)
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