Nandhakumar Kanagarajan

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OBJECTIVE We evaluated the disease modifying effect of simvastatin and atorvastatin in Dextran Sulfate Sodium (DSS) model of colitis. MATERIALS AND METHODS Thirty, 8-week old female Swiss-Webster mice were separated into 5 groups (n = 6/group). Colitis was induced by feeding 4 % DSS solution for 7 days. Following discontinuation of DSS, over the next 7(More)
Background. The prevalence of fecal incontinence varies tremendously as a result of inadequate data collection methods. Few office-based studies have assessed the prevalence of fecal incontinence and none have looked at modifiable risk factors or effect on quality of life. Design, Settings, Patients, and Main Outcome Measures. Five hundred patients who(More)
Ischemic reperfusion injury due to oxidative stress remains one of the challenging problems during cardiac surgeries. The imbalance in the production of free radicals and antioxidants in vivo determines the extent of oxidative stress. The use of antioxidants in cardioplegia has become an important strategy to salvage the myocardium from the attack of these(More)
OBJECTIVES Patients have previously expressed preference for the gender of their endoscopist. Most of these patients were Caucasian women of predominantly high socioeconomic status. No study has evaluated the gender preferences of both women and men from a diverse but predominantly low socioeconomic background. The aim of this study was to evaluate gender(More)
Obesity in the United States poses a tremendous health risk to approximately one third of the population. As this epidemic grows, the number of bariatric surgeries performed will also increase. Although obesity itself is not gender specific, 85% of bariatric surgeries are performed in women. This article reviews some of the commonly performed(More)
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