Nanda Kumar N. Shanmugam

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The cyclooxygenase-2 (PTGS2, previously known as COX2) enzyme and its products, such as prostaglandin E2 (PGE2), have been implicated in the pathogenesis of several inflammatory diseases including(More)
The liver hormone hepcidin is the central regulator of systemic iron metabolism. Its increased expression in inflammatory states leads to hypoferremia and anemia. Elucidation of the mechanisms that(More)
Gut commensal bacteria contribute to the pathogenesis of inflammatory bowel disease, in part by activating the inflammasome and inducing secretion of interleukin-1ß (IL-1ß). Although much has been(More)