Nancy C Snidman

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We investigated the hypothesis that beat-to-beat variability in hemodynamic parameters reflects the dynamic interplay between ongoing perturbations to circulatory function and the compensatory response of short-term cardiovascular control systems. Spontaneous fluctuations in heart rate (HR), arterial blood pressure, and respiration were analyzed by spectral(More)
This study tested the hypothesis that very young children who received more morphine for acute burns would have larger decreases in posttraumatic symptoms 3 to 6 months later. This has never before been studied in very young children, despite the high frequency of burns and trauma in this age group. Seventy 12- to 48-month-old nonvented children with acute(More)
Measures of EEG spectral power, lateral asymmetry in the frontal and parietal areas, and social behavior with an examiner were analyzed on 166 children, 10 to 12 years old, who were participating in a longitudinal study of the temperamental contributions to social behavior. Loss of 8- to 13-Hz power (alpha band) on the right, compared with the left, frontal(More)
CONTEXT The term temperament refers to a biologically based predilection for a distinctive pattern of emotions, cognitions, and behaviors first observed in infancy or early childhood. High-reactive infants are characterized at age 4 months by vigorous motor activity and crying in response to unfamiliar visual, auditory, and olfactory stimuli, whereas(More)
Four-month-old infants from Boston, Dublin, and Beijing were administered the same battery of visual, auditory, and olfactory stimuli to evaluate differences in level of reactivity. The Chinese infants were significantly less active, irritable, and vocal than the Boston and Dublin samples, with American infants showing the highest level of reactivity. The(More)
OBJECTIVE Symptoms of posttraumatic stress disorder (PTSD) are a focus of much research with older children, but little research has been conducted with young children, who account for about 40% of all pediatric burn injuries. This is a longitudinal study of 72 acutely burned children (12-48 months old) that assessed the course of acute posttraumatic(More)
The purpose of this study was to assess the role of trauma severity on subsequent symptoms of posttraumatic stress disorder (PTSD) and physiological reactivity in a total of 70 children, ranging from 12 to 48 months of age, who were acutely burned. Parents were interviewed shortly after the child was admitted to the hospital. PTSD symptoms were measured(More)
BACKGROUND Behavioral inhibition to the unfamiliar (BI) is a heritable temperamental phenotype involving the tendency to display fearful, avoidant, or shy behavior in novel situations. BI is a familial and developmental risk factor for panic and phobic anxiety disorders. We previously observed an association between BI and a microsatellite marker linked to(More)