Nan Tang

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The present study investigated the effects of 2-(1-hexyloxyethyl)-2-devinylpyro pheophorbide-a (HPPH)-mediated photodynamic therapy (PDT) on in vitro cell survival and in vivo tumor growth derived from human esophageal squamous cancer cells (Eca109). A cell counting kit 8 (CCK8) assay was used to assess the phototoxicity of HPPH-mediated PDT in cultured(More)
MEK/extracellular signal-regulated kinase (ERK) mitogen-activated protein kinase signaling is imperative for proper chemotaxis. Dictyostelium mek1 ؊ (MEK1 null) and erk1 ؊ cells exhibit severe defects in cell polarization and directional movement, but the molecules responsible for the mek1 ؊ and erk1 ؊ chemotaxis defects are unknown. Here, we describe a(More)
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