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The oligodendrocyte lineage genes Olig1 and Olig2 encode related bHLH proteins that are coexpressed in neural progenitors. Targeted disruption of these two genes sheds light on the ontogeny of oligodendroglia and genetic requirements for their development from multipotent CNS progenitors. Olig2 is required for oligodendrocyte and motor neuron specification(More)
A two-terminal interactive distributed source coding problem with alternating messages for function computation at both locations is studied. For any number of messages, a computable characterization of the rate region is provided in terms of single-letter information measures. While interaction is useless in terms of the minimum sum-rate for lossless(More)
A problem of interactive function computation in a collocated network is studied in a distributed block source coding framework. With the goal of computing samples of a desired function of sources at the sink, the source nodes exchange messages through a sequence of error-free broadcasts. For any function of independent sources, a computable(More)
The paper attempts to provide an alternative method for measuring the importance of scientific papers based on the Google’s PageRank. The method is a meaningful extension of the common integer counting of citations and is then experimented for bringing PageRank to the citation analysis in a large citation network. It offers a more integrated picture of the(More)
A two-terminal interactive function computation problem with alternating messages is studied within the framework of distributed block source coding theory. For any finite number of messages, a single-letter characterization of the sum-rate-distortion function was established in previous works using standard information-theoretic techniques. This, however,(More)
Engraftment of mesenchymal stem cells (MSCs) derived from adult bone marrow has been proposed as a potential therapeutic approach for postinfarction left ventricular dysfunction. However, limited cell viability after transplantation into the myocardium has restricted its regenerative capacity. In this study, we genetically modified MSCs with an(More)
A complex structure, designated the chromosome periphery, surrounds each chromosome during mitosis. Although several proteins have been shown to localize to the chromosome periphery, their functions during mitosis remain unclear. Here, we used a combination of high-resolution microscopy and RNA-interference-mediated depletion to study the functions of(More)
PURPOSE Intraocular injections of vascular endothelial growth factor (VEGF), a peptide implicated in the pathogenesis of diabetic retinopathy, can induce retinal ischemia. Diabetic retinal ischemia may be caused, in part, by the adhesion of leukocytes to the retinal vasculature. In this study, the ability of VEGF to increase the expression of intercellular(More)
The problem of reconstructing a source sequence with the presence of decoder side-information that is mis-synchronized to the source due to deletions is studied in a distributed source coding framework. Motivated by practical applications, the deletion process is assumed to be bursty and is modeled by a Markov chain. The minimum rate needed to reconstruct(More)
INTRODUCTION Neuregulin-1 (NRG1) is one of susceptibility genes for schizophrenia and plays critical roles in glutamatergic, dopaminergic and GABAergic signaling. Using mutant mice heterozygous for Nrg1 (Nrg1(+/-)) we studied the effects of Nrg1 signaling on behavioral and electrophysiological measures relevant to schizophrenia. EXPERIMENTAL PROCEDURE(More)