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BACKGROUND Inadequate extracellular conditions can adversely affect the environment of the ER and impinge on the maturation of nascent proteins. The resultant accumulation of unfolded proteins activates a signal transduction pathway, known as the unfolded protein response, which serves primarily to protect the cell during stress and helps restore(More)
Due to its excellent device features, manufacture process compatibility and diversity of the circuit structures, The FinFET is considered appropriate candidate for the conventional bulk-MOSFET in sub-22nm technology nodes. However, the power estimation CAD tools for FinFET are missing at the moment, which mainly results from the absence of FinFET power(More)
With the aggressive scaling of device technology, the leakage power has become the main part of power consumption, which seriously reduces the energy recovery efficiency of adiabatic logic. In this paper, a novel low-power adiabatic logic based on FinFET devices has been proposed. Due to the lower leakage current, higher on-state current and design(More)
FinFET, because of good device characteristics, manufacture process compatibility and the diversity of the circuit structure, is considered the best candidate for the conventional bulk-MOSFETs in sub-22nm technology nodes. In this paper, power model of multi-mode FinFET standard cells are discussed and the influence that back-gate voltage of FinFETs on(More)
BACKGROUND The unfolded protein response (UPR) is regulated by three ER-localized, transmembrane signal transducers that control distinct aspects of the UPR. We previously reported that both increased resistance to etoposide and a reduction in Topoisomerase IIα protein levels were a direct response of UPR activation, and the latter occurred independent of(More)
With the technology scaling down, low power dissipation has become one of the research focuses in the field of integrated circuit design. Various types of adiabatic logics have been invented for low-power applications. However, the expanding leakage current degrades the performance of conventional adiabatic logics. In this article, a novel improved(More)