Namshik Han

Zongling Ji3
Aaron Webber3
Xi Chen2
Andrew D. Sharrocks2
3Zongling Ji
3Aaron Webber
2Xi Chen
2Andrew D. Sharrocks
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CONTEXT Cortisol is released in ultradian pulses. The biological relevance of the resulting fluctuating cortisol concentration has not been explored. OBJECTIVE Determination of the biological consequences of ultradian cortisol pulsatility. DESIGN A novel flow through cell culture system was developed to deliver ultradian pulsed or continuous cortisol to(More)
There are numerous forkhead transcription factors in mammalian cells but we know little about the molecular functions of the majority of these. FOXK2 is a ubiquitously expressed family member suggesting an important function across multiple cell types. Here, we show that FOXK2 binds to the SIN3A and PR-DUB complexes. The PR-DUB complex contains the(More)
After publication of this study [1], we discovered that we had unintentionally omitted to include an accession number for our ChIP-seq data. The ChIP-seq data for FOXM1 in OE33 cells is available at ArrayExpress; accession number E-MTAB-4121. In addition, we omitted to include lists of the high confidence and high coverage FOXM1 binding regions. This has(More)
Survival rates for oesophageal adenocarcinoma (OAC) remain disappointingly poor and current conventional treatment modalities have minimal impact on long-term survival. This is partly due to a lack of understanding of the molecular changes that occur in this disease. Previous studies have indicated that the transcription factor FOXM1 is commonly upregulated(More)
Analyzing protein-RNA binding structures depends on a significant quantity of manual work. Therefore, the protein-RNA binding structures are generally studied individually or on a small-scale. The task of analyzing the protein-RNA binding structures manually becomes increasingly difficult as the complexity and number of protein-RNA binding structures(More)
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