Naim Kittana

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The purpose of this study was to evaluate the weight uniformity of some commonly divided tablets produced by Palestinian Pharmaceutical companies. Volunteers were asked to divide scored tablets. The split units were individually weighed and the relative standard deviation for each product was calculated. Five scored tablet products failed the United States(More)
BACKGROUND Treatment of neuropathic pain has always been challenging, not only from the pharmaco-therapeutic/toxicological point of view, but also due to the unpredictable pharmacokinetic (PK) variations among different generic formulations of the same drug, which require further dose optimization. OBJECTIVES This progressive work aims to evaluate the(More)
PURPOSE Ephedra alata (E. alata) is perennial tough shrub plant that grows in Palestine and other regions. It is used often in folk's medicine for the treatment of various diseases. In this project, E. alata extract was tested for its ability to improve wound and burn healing. METHODS An aqueous extract of E. alata was prepared and underwent several(More)
PURPOSE The stability of an extemporaneously prepared rosuvastatin suspension stored over 30 days under various storage conditions was evaluated. METHODS Rosuvastatin suspension was extemporaneously prepared using commercial rosuvastatin tablets as the source of active pharmaceutical ingredient. The organoleptic properties, dissolution profile, and(More)
Cardiac remodeling (cardiac hypertrophy and fibrosis) is a hall mark of heart failure (HF). It can be induced by the abnormal elevation of several endogenous factors including angiotensin II (Ang II), which is generated from its precursor angiotensin I (Ang I) by the action of angiotensin converting enzyme (ACE). The inhibition of this enzyme or the(More)
INTRODUCTION Montelukast is recommended for the treatment of asthma, exercise -induced bronchospasm and allergic rhinitis. Several trials demonstrated potential therapeutic effects in other respiratory conditions, and different animal-model-based studies explored potential pharmacological actions in non-respiratory conditions. AREAS COVERED Clinical(More)
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