Naila Irum Hadi

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UNLABELLED Breast cancer is a global health issue, and as the tumor burden increases, we need to come up with newer, better technologies which are convenient, cheap, rapid, sensitive with a high specificity. Technological advancements in the field of cancer biomarker has led to the development of techniques such as mass spectrometric analysis and microarray(More)
On the basis of mucin content all cases were divided into mucinous (MUC; n = 14; 20%) and nonmucinous (nMUC; n = 56; 80%) adenocarcinomas. The predominant mucin on histochemistry of colorectal adenocarcinoma ( nMUC and MUC) was sialomucin. Tumors were further graded histologically into low-grade (85.71%) and high-grade (14.28%). MUC adenocarcinoms showed a(More)
OBJECTIVE To record various clinicopathological characteristics of breast cancer (BC) in our population and to find an association between these characteristics and axillary nodal metastasis. METHODS This cross-sectional study included 150 BC patients from two tertiary care centers in Karachi from 15(th) February, 2013 to 31(st) March, 2015. Frequencies,(More)
Detection of metabolic signature for breast cancer (BC) has the potential to improve patient prognosis. This study identified potentially significant metabolites differentiating between breast cancer patients and healthy controls to help in diagnosis, grading, staging and determination of neoadjuvant status. Serum was collected from 152 pre-operative breast(More)
BACKGROUND Breast cancer (BC) is a major health issue worldwide as well as in Pakistan. All women belonging to any race, ethnicity or lineage are in danger of developing breast cancer. Significant factors influencing the development of breast malignancies are the genetic background, environmental conditions, reproductive parameters, the consequences of(More)
All normal colorectal mucosa samples expressed MUC2 but did not show MUC1 and MUC5AC expression. MUC1 expression was found in 15% of tumors originating mostly from proximal colon and were Dukes’ stage C lesions. Less frequent expression was seen in MUC adenocarcinoma (25%), with no expression in signet ring cell carcinoma. MUC2 expression was found in 55%(More)
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