Nai-Wen Chang

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MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 nucleotides, which negatively regulate the gene expression at the post-transcriptional level. This study describes an update of the miRTarBase (http://miRTarBase.mbc.nctu.edu.tw/) that provides information about experimentally validated miRNA-target interactions (MTIs). The latest update of(More)
Bidens pilosa (B. pilosa) is well known in Taiwan as a traditional Chinese medicine. The purpose of this study was to evaluate the ability of both the ethanol (EtOH) and ethylacetate/ethanol (EA/EtOH) extracts from the whole B. pilosa plant, to protect normal human erythrocytes against oxidative damage in vitro. It was determined that the oxidative(More)
Given a graph and a non-negative integer , the -extra connectivity (resp. -extra edge connectivity) of is the minimum cardinality of a set of vertices (resp. edges) in , if it exists, whose deletion disconnects and leaves each remaining component with more than vertices. This study shows that the 3-extra connectivity (resp. 3-extra edge connectivity) of an(More)
In this paper, the trajectory tracking and (dynamic) obstacle avoidance of a car-like mobile robot (CLMR) within distributed sensor-network spaces via fuzzy decentralized sliding-mode control (FDSMC) is developed. To implement trajectory tracking and (dynamic) obstacle avoidance, two distributed charge-coupled device (CCD) cameras are set up to realize the(More)
AIMS Epidermal growth factor receptor pathway substrate 8 (Eps8) is a signaling protein implicated in the development of many human cancers including oral squamous cell carcinoma (OSCC). This study examined the expression of Eps8 and assessed its significance in patients with OSCC. METHODS Immunohistochemical staining for Eps8 was conducted in 205 cases(More)
Processor fault diagnosis plays an important role in measuring the reliability of multiprocessor systems and the diagnosis of many well-known interconnection networks. The conditional diagnosability, which is more general than the classical diagnosability, is to measure the diagnosability of a multiprocessor system under the assumption that all of the(More)
Processor fault diagnosis has played an important role in measuring the reliability of a multiprocessor system, and the diagnosability of many well-known multiprocessor systems has been widely investigated. The conditional diagnosability is a novel measure of diagnosability by adding an additional condition that any faulty set cannot contain all the(More)
The objective of this study was to investigate the fermented culture broth of Antrodia camphorata (A. camphorata) to induce apoptosis and inhibit cyclooxygenase-2 (COX-2) in estrogen-nonresponsive (MDA-MB-231) human breast cancer cells. Treatment of the highly invasive MDA-MB-231 cells with A. camphorata (40-240 microg/ml) resulted in dose and(More)