Nagaraja Sethuraman

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The development of efficient germ-line transformation technologies for mosquitoes has increased the ability of entomologists to find, isolate and analyze genes. The utility of the currently available systems will be determined by a number of factors including the behavior of the gene vectors during the initial integration event and their behavior after(More)
The post-integration activity of piggyBac transposable element gene vectors in Aedes aegypti mosquitoes was tested under a variety of conditions. The embryos from five independent transgenic lines of Ae. aegypti, each with a single integrated non-autonomous piggyBac transposable element gene vector, were injected with plasmids containing the piggyBac(More)
The cinnabar gene of Drosophila melanogaster (Meigen) encodes for kynurenine hydroxylase, an enzyme involved in ommochrome biosynthesis. This gene is commonly included as a visible genetic marker in gene vectors used to create transgenic Aedes aegypti (L.) that are homozygous for the khw allele, the mosquito homolog of cinnabar. Unexpectedly, the phenotype(More)
(2003). Gene vector and transposable element behavior in mosquitoes. A paper by Adelman et al. was incorrectly cited in the text and Reference list as 'in press' in Genetics. The article has actually been submitted elsewhere. The authors apologise for any inconvenience this may have caused. Corrigendum 1263 Creating the technology to produce transgenic(More)
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