Nadjia Kachenoura

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Arterial stiffness predicts cardiovascular events beyond traditional risk factors. However, the relationship with aging of novel noninvasive measures of aortic function by MRI and their interrelationship with established markers of vascular stiffness remain unclear and currently limit their potential impact. Our aim was to compare age-related changes of(More)
A computer-assisted method is proposed to estimate transmural extent of myocardial infarction. In 40 patients with chronic myocardial infarction and 3 control subjects, late gadolinium enhancement images were acquired with magnetic resonance imaging. Segmental infarct transmural extent was visually assessed by two experts on a 5-point scale. A fuzzy c-means(More)
Although the ability of multi-detector computed tomography (MDCT) to detect perfusion abnormalities associated with acute and chronic myocardial infarction (MI) has been demonstrated, this methodology is based on visual interpretation of selected 2D slices. We sought to develop a new technique for quantitative volumetric analysis of myocardial perfusion(More)
PURPOSE To assess if segmentation of the aorta can be accurately achieved using the modulus image of phase contrast (PC) magnetic resonance (MR) acquisitions. MATERIALS AND METHODS PC image sequences containing both the ascending and descending aorta of 52 subjects were acquired using three different MR scanners. An automated segmentation technique, based(More)
OBJECTIVES We sought to define age-related geometric changes of the aortic arch and determine their relationship to central aortic stiffness and left ventricular (LV) remodeling. BACKGROUND The proximal aorta has been shown to thicken, enlarge in diameter, and lengthen with aging in humans. However, no systematic study has described age-related(More)
Multidetector computed tomography (MDCT) is increasingly used as an alternative to invasive coronary angiography. Although computed tomographic coronary angiography (CTCA) has been validated against invasive coronary angiography and nuclear myocardial perfusion imaging, the potential of MDCT to evaluate perfusion has not been fully explored. We sought to(More)
BACKGROUND The predictive value of ascending aortic distensibility (AAD) for mortality and hard cardiovascular disease (CVD) events has not been fully established. OBJECTIVES This study sought to assess the utility of AAD to predict mortality and incident CVD events beyond conventional risk factors in MESA (Multi-Ethnic Study of Atherosclerosis). (More)
The computerized study of the regional contraction of the left ventricle has undergone numerous developments, particularly in relation to echocardiography. A new method, parametric analysis of main motion (PAMM), is proposed in order to synthesize the information contained in a cine loop of images in parametric images. PAMM determines, for the intensity(More)
The aim of this paper is to develop an automated method which operates on echocardiographic dynamic loops for classifying the left ventricular regional wall motion (RWM) in a four-point scale. A non-selected group of 37 patients (2 and 4 chamber views) was studied. Each view was segmented according to the standardized segmentation using three manually(More)