Nadine Meunier

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OBJECTIVE Inadequate intakes of micronutrients in elderly negatively affect the nutritional status. Zinc is an essential micronutrient in the elderly, especially in relation to its impact on immune function, bone mass, cognitive function and oxidative stress. However, data are lacking on zinc intake and status during normal ageing. In this study, we(More)
BACKGROUND To investigate the improvement in quality of life (QoL) of alcohol-dependent patients during a 3-week inpatient withdrawal programme, and to identify the sociodemographic, clinical and alcohol-related variables associated with baseline QoL on admission and with improvement of QoL during residential treatment. METHODS This prospective,(More)
The elderly are at nutritional risk as a result of multiple physiological, social, psychological, and economic factors. Physiological functions naturally decline with age, which may influence absorption and metabolism. Social and economic conditions can adversely affect dietary choices and eating patterns. However, at the same time, the nutrient needs of(More)
OBJECTIVE To report selected dietary intake and vitamin status at baseline of volunteers participating in the ZENITH study and the correlation of vitamin status with zinc. DESIGN A multicentre prospective intervention study employing a randomised double-blind design. SETTING Clermont-Ferrand, Theix (France), Coleraine (Northern Ireland), Grenoble(More)
OBJECTIVE Baseline data are reported from a study of the effects of zinc supplementation on cognitive function in older adults as assessed by the CANTAB computerised test battery. DESIGN This is a multicentre prospective intervention study employing a randomised double-blind design. SETTING European community-based study. PARTICIPANTS There are 387(More)
BACKGROUND Adjustments in intestinal absorption and losses of zinc (Zn) are thought to maintain Zn homeostasis when dietary intake levels are altered. Zn status may also influence efficiency of intestinal Zn absorption. OBJECTIVES To determine the impact of dietary intake and status of some micronutrients on Zn absorption in late middle-aged men. DESIGN(More)
OBJECTIVE To investigate the relationship between indices of zinc nutritive status and biochemical markers of bone turnover in older adult European subjects. DESIGN Use of baseline data from a multicentre prospective zinc intervention (ZENITH) study. SETTING Centres in France, Italy and Northern Ireland. PARTICIPANTS A total of 387 healthy adults,(More)
OBJECTIVE Oxidative stress has been reported to increase with ageing. However, the data in healthy humans remain controversial and studies in free-living elderly people are scarce. The objective of the present study was to compare age-related oxidative stress in late middle-aged and older free-living subjects. DESIGN The effect of ageing on oxidative(More)
BACKGROUND Age-related decline in taste acuity may be both a cause and an effect of depleted zinc and/or increased zinc requirement. OBJECTIVE The aim of this study was to explore associations between zinc status and taste acuity in healthy older European adults aged 55-90 y. SAMPLE Volunteers were recruited within Italy (n = 108 aged 70-90 y), the(More)
BACKGROUND/OBJECTIVES Data from human studies that have investigated the association between vitamin D status and cognitive function in elderly adults are conflicting. The objective of this study was to assess vitamin D status (reflected by serum 25-hydroxyvitamin D (25(OH)D)) in older European subjects (n=387; aged 55-87 years) and examine its association(More)