Nadine Aubry

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It is well established that the aging heart exhibits left ventricular (LV) diastolic dysfunction and changes in mechanical properties, which are thought to be due to alterations in the extracellular matrix. We tested the hypothesis that the mechanical properties of cardiac myocytes significantly change with aging, which could contribute to the global(More)
We experimentally study the transient clustering behavior of viable yeast cells in a dilute suspension suddenly subjected to a nonuniform alternating current (AC) electric field of a microelectrode device. The frequency of the applied electric field is varied to identify two distinct regimes of positive dielectrophoresis. In both regimes, the yeast cells(More)
Based on the transport model of Sorensen et al. [1, 2], an improved mathematical model describing the process of thrombus deposition and growth was developed. Blood is treated as a multi-constituent mixture comprised of a linear fluid phase and a thrombus phase. The transport and reactions of 10 chemical and biological species are modeled using a system of(More)
Continuous flow ventricular assist devices (cfVADs) provide a life-saving therapy for severe heart failure. However, in recent years, the incidence of device-related thrombosis (resulting in stroke, device-exchange surgery or premature death) has been increasing dramatically, which has alarmed both the medical community and the FDA. The objective of this(More)
The analysis of physical datasets using modern methods developed in machine learning presents unique challenges and opportunities. These datasets typically feature many degrees of freedom, which tends to increase the computational cost of statistical methods and complicate interpretation. In addition, physical systems frequently exhibit a high degree of(More)
The use of microscopic discrete fluid volumes (i.e., droplets) as microreactors for digital microfluidic applications often requires mixing enhancement and control within droplets. In this work, we consider a translating spherical liquid droplet to which we impose a time periodic rigid-body rotation which we model using the superposition of a Hill vortex(More)
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