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Ancient Admixture in Human History
Population mixture is an important process in biology. We present a suite of methods for learning about population mixtures, implemented in a software package called ADMIXTOOLS, that support formalExpand
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A High-Coverage Genome Sequence from an Archaic Denisovan Individual
Ancient Genomics The Denisovans were archaic humans closely related to Neandertals, whose populations overlapped with the ancestors of modern-day humans. Using a single-stranded library preparationExpand
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Massive migration from the steppe was a source for Indo-European languages in Europe
We generated genome-wide data from 69 Europeans who lived between 8,000–3,000 years ago by enriching ancient DNA libraries for a target set of almost 400,000 polymorphisms. Enrichment of theseExpand
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The Simons Genome Diversity Project: 300 genomes from 142 diverse populations
Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are notExpand
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Genome-wide patterns of selection in 230 ancient Eurasians
Ancient DNA makes it possible to observe natural selection directly by analysing samples from populations before, during and after adaptation events. Here we report a genome-wide scan for selectionExpand
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Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture.
Improvements in technology have reduced the cost of DNA sequencing to the point that the limiting factor for many experiments is the time and reagent cost of sample preparation. We present anExpand
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Genetic analyses from ancient DNA.
About 20 years ago, DNA sequences were separately described from the quagga (a type of zebra) and an ancient Egyptian individual. What made these DNA sequences exceptional was that they were derivedExpand
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Ancient human genomes suggest three ancestral populations for present-day Europeans
We sequenced genomes from a ∼7,000 year old early farmer from Stuttgart in Germany, an ∼8,000 year old hunter-gatherer from Luxembourg, and seven ∼8,000 year old hunter-gatherers from southernExpand
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Genomic insights into the origin of farming in the ancient Near East
We report genome-wide ancient DNA from 44 ancient Near Easterners ranging in time between ~12,000 and 1,400 bc, from Natufian hunter–gatherers to Bronze Age farmers. We show that the earliestExpand
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Ancient DNA extraction from bones and teeth
This method is designed to maximize recovery of PCR-amplifiable DNA from ancient bone and teeth specimens and at the same time to minimize co-extraction of substances that inhibit PCR. This isExpand
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