Nadia I Kihiczak

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Blistering is a common occurrence generally caused by moderate or repetitive trauma to the skin. Blistering due to minor trauma is less common and may be associated with a group of heterogeneous genetic diseases called epidermolysis bullosa (EB). The level of vesiculation within the skin defines 3 major subtypes of EB: EB simplex (EBS), dystrophic EB, and(More)
Seborrheic keratoses (SKs) are common benign nonmelanocytic epidermal tumors with characteristic clinical features, which are thought to allow a straightforward diagnosis in most situations. As a result, it is an accepted practice to destroy them without histopathologic confirmation. However, systematic reviews of histologic specimens reveal an erroneous(More)
In this work we will discuss three cutaneous markers of systemic disease. Acanthosis nigricans is the most widely known in this category. Cutaneous angiokeratomas are usually associated with enzyme defect disorders, such as Fabry's disease, and are linked in this work as a reactive pattern in hepatorenal failure. Mast cell disease may occur in a number of(More)
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