Nadia Bouarioua

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BACKGROUND Several database studies report a lack of care in elderly patients with colorectal cancer. PURPOSE To describe the management of elderly patients admitted for colorectal cancer; to identify factors associated with standard management according to recommendations and to study factors influencing the survival. PATIENTS AND METHODS All(More)
INTRODUCTION Squamous cell carcinoma SCC of the rectum is a distinct entity. We report a very rare case of squamous cell carcinoma of the middle rectum. PRESENTATION OF CASE The patient was a 62-year-old woman who presented with a history of rectal bleeding and discomfort. Colonoscopy revealed a polypoid tumour of the middle rectum. Biopsies of this mass(More)
RAS mutation status is an important prognostic factor after resection of liver metastases (LiM) from colorectal cancer (CRC). The prognostic significance of RAS after resection of lung (LuM) and peritoneal (PM) metastases from CRC is unknown. Between 2005 and 2014, all consecutive patients with known RAS status who underwent potentially curative resection(More)
INTRODUCTION Data about the expression of Epidermal Growth Factor Receptors (EGFRs) in colorectal adenomas remain scarce. RESULTS 101 patients were enrolled including 53 controls. All adenomas (n = 38) and CRC (n = 5) were EGFR positive. Hyperplastic polyps (HP) (n = 8) and control colons (n = 53) were EGFR negative in half of cases (p < 0.0001). A well(More)
INTRODUCTION Patients with metastatic or locally advanced, non-resectable, grade 1 or 2 well-differentiated duodeno-pancreatic (WDDP) NETs are treated following European guidelines. Patients (Pts) with aggressive disease, i.e. progressive and/or symptomatic metastases and/or with significant hepatic invasion (>30-50%), and/or bone metastases, anti-tumour(More)
INTRODUCTION Use of sorafenib remains debated in elderly patients treated for advanced hepatocellular carcinoma (HCC). METHODS This was a bicentric retrospective study including all patients ≥75years and treated with sorafenib for advanced HCC between January 2010 and March 2014. RESULTS Of the 51 patients included (median age: 78 years, range: 75-92;(More)
La chimiothérapie des cancers colorectaux a été profondément modifiée ces dernières années. Alors même que la place respective de l’irinotécan et de l’oxaliplatine n’était pas complètement définie, les thérapies ciblées sont arrivées. De nombreuses questions de stratégie thérapeutique restent non résolues, mais des informations scientifiques récentes(More)
L’intensité de la réponse tumorale en première ligne du cancer colorectal métastatique conditionne non seulement la résécabilité secondaire des métastases, mais aussi les stratégies d’après induction (pause, entretien). La profondeur de la réponse tumorale pourrait par ailleurs conditionner l’action des antiangiogéniques dont l’efficacité serait(More)
UNLABELLED Comprehensive geriatric assessment (CGA) is advocate to improved care of elderly with cancer but is not available in every hospital within a short delay. Therefore, a tool allowing gastroenterologist to detect rapidly specific abnormalities in elderly is needed. PATIENTS AND METHODS the aim of our pilot study was to evaluate feasibility of a(More)