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OBJECTIVE To identify intrapartum predictors of newborn encephalopathy in term infants. DESIGN Population based, unmatched case-control study. SETTING Metropolitan area of Western Australia, June 1993 to September 1995. SUBJECTS All 164 term infants with moderate or severe newborn encephalopathy; 400 randomly selected controls. MAIN OUTCOME MEASURES(More)
OBJECTIVE To ascertain antepartum predictors of newborn encephalopathy in term infants. DESIGN Population based, unmatched case-control study. SETTING Metropolitan area of Western Australia, June 1993 to September 1995. SUBJECTS All 164 term infants with moderate or severe newborn encephalopathy; 400 randomly selected controls. MAIN OUTCOME MEASURES(More)
Neonatal encephalopathy (NE) is the clinical manifestation of disordered neonatal brain function. Lack of universal agreed definitions of NE and the sub-group with hypoxic-ischaemia (HIE) makes the estimation of incidence and the identification of risk factors problematic. NE incidence is estimated as 3.0 per 1000 live births (95%CI 2.7 to 3.3) and for HIE(More)
OBJECTIVE Robin sequence (RS) is associated with airway abnormalities that result in functional problems of obstructive sleep apnoea (OSA), feeding difficulties, and consequent poor growth. We evaluated the relationships between OSA severity, airway and feeding interventions, and weight at 12 months in infants with RS and OSA. METHODS Retrospective notes(More)
OBJECTIVE The aim of this study was to ascertain the early developmental status of children who have a history of newborn encephalopathy. METHODS A longitudinal follow-up was conducted of a population-based, case-control study of children born in Western Australia between June 1993 and December 1996. The study included 276 term children (>/=37 weeks'(More)
PURPOSE The aim of the study was to describe the incidence and survival of infants born with congenital diaphragmatic hernia (CDH) in the state of New South Wales (NSW) and the Australian Capital Territory (ACT), Australia. METHODS A population-based cohort study of all infants inclusive up to 1 month of age diagnosed with CDH in NSW and the ACT between(More)
Between June 1993 and December 1996, 276 term newborn infants with encephalopathy and 564 randomly selected term controls were enrolled in a population-based study of moderate and severe term newborn encephalopathy (NE) in Western Australia. During comprehensive neurobehavioural and cognitive follow-up of all patients and controls at 3 years and again at 5(More)
BACKGROUND The aetiology of preterm birth is complex and there is evidence that subclinical genital tract infection influences preterm labour in some women but the role of prophylactic antibiotic treatment in the management of preterm labour is controversial. Since rupture of the membranes is an important factor in the progression of preterm labour, it is(More)
Cerebral palsy (CP) is a term of convenience applied to a group of motor disorders of central origin defined by clinical description. It is not a diagnosis in that its application infers nothing about pathology, aetiology, or prognosis. It is an umbrella term covering a wide range of cerebral disorders which result in childhood motor impairment. The precise(More)
OBJECTIVE To compare cardiotocograph (CTG) records during labour in cases of neonatal encephalopathy and matched controls. DESIGN Case-control study. SETTING Metropolitan area of Perth, Western Australia. SUBJECTS Term deliveries complicated by neonatal encephalopathy and controls matched for sex, hospital, time of birth, day of week of birth and(More)