Learn More
Mucopolysaccharidosis type IV (MPSIV), also known as Morquio syndrome, is a progressive genetic condition which predominantly affects skeletal development. Research thus far has focused on physical manifestations, with little attention to psychological characteristics. As a first step in determining the natural occurrence of psychological symptoms in this(More)
  • Nadia K. Ali
  • Journal of community hospital internal medicine…
  • 2012
INTRODUCTION A third of Americans have low health literacy (HL). Research indicates a significant knowledge and skills gap among residents pertaining to management of patients with low HL. OBJECTIVES The objective of this study was to assess the teaching and evaluation methods around HL in community-based internal medicine residency programs. In addition,(More)
We report an experiment which seeks to determine how novice users’ conceptual understanding of graphs differs depending on the nature of the interaction with them. Undergraduate psychology students were asked to interpret three-variable “interaction” data in either bar or line graph form and were required to either think aloud while doing so or to produce(More)
Malignant phyllodes tumors (MPT) are exceptionally rare, and the genomic drivers of these tumors are still being elucidated. We performed comprehensive genomic profiling (CGP) of MPT to identify genomic alterations that will inform approaches to targeted therapy for patients with MPT, including relapsed, refractory, and metastatic disease. DNA was extracted(More)
OBJECTIVES Precise characterization of cognitive outcomes and factors that contribute to cognitive variability will enable better understanding of disease progression and treatment effects in mucopolysaccharidosis type I (MPS I). We examined the effects on cognition of phenotype, genotype, age at evaluation and first treatment, and somatic disease burden.(More)
UNLABELLED The lysosomal enzyme α-L-iduronidase hydrolyzes terminal iduronic acid from heparan sulfate and dermatan sulfate, and is an essential step in GAG degradation. Mutations of its gene, IDUA, yield a spectrum of mucopolysaccharidosis (MPS) type I clinical disorders. The IDUA mutation, c.712T>A (p.L238Q) was previously noted as a mild mutation. In a(More)
BACKGROUND Medical trainees infrequently use health literacy (HL) skills and overestimate their use of plain language and teach back skills. The aim of this study is to assess if level of training impacts the perception of medical trainees around HL knowledge and skills. METHODS A structured questionnaire consisting of 5 questions assessing the(More)
OBJECTIVE We report three experiments investigating the ability of undergraduate college students to comprehend 2 x 2 "interaction" graphs from two-way factorial research designs. BACKGROUND Factorial research designs are an invaluable research tool widely used in all branches of the natural and social sciences, and the teaching of such designs lies at(More)
Hospital Physician February 2009 C hronic obstructive pulmonary disease (COPD) is a common chronic disease with high mor­ bidity and mortality worldwide. A recent study conducted to determine the global burden of COPD using recent diagnostic criteria1 estimated that the prevalence of moderate to severe COPD is 10.1%.2 A large percentage of these individuals(More)
Fabry disease (FD) is a genetic X-linked, multisystemic, progressive lysosomal storage disorder (LSD). Depression has emerged as a disease complication, with prevalence estimates ranging from 15 to 62%. This is a pilot study examining the effects of psychological counseling for depression in FD on depression, adaptive functioning (AF), quality of life(More)