Nadeem Hashem

Learn More
Xeroderma pigmentosum (XP) has been reported to be unusually frequent among Middle Eastern populations. This report describes the first survey of DNA repair characteristics among Egyptians. Sixteen XP patients were contacted, and biopsies from eight were analyzed for unscheduled DNA synthesis, strand breakage during pyrimidine dimer excision, and(More)
The development of contact allergy in sun-exposed skin is markedly impaired in patients with xeroderma pigmentosum as compared to the responses in healthy control subjects. The degree of this immunological impairment is directly related to the severity of the cutaneous disease. These findings raise the possibility that sunlight-induced alterations of immune(More)
Xeroderma pigmentosum (XP) occurs with high frequency in Egypt and a continuation of our field studies has identified representatives of the 3 major complementation groups A, C, and variant. Group A patients, with one exception, showed very early onset of sun sensitivity and development of skin cancers, and microcephaly and mental retardation. The(More)
Acoustic tumors are one of the common problems that both the otologist and the neurosurgeon face in Egypt. Early diagnosis and choice of surgical approach--whether middle fossa, translabyrinthine, or suboccipital--are discussed after review of forty-one cases of cerebellopontine angle masses we have seen over the last fifteen years. Particular attention is(More)
Laboratory ware for the in vitro-produced embryos is generally made from embryo-tested plastic instead of glass. The quality of the plastic is crucial for the outcome because plastic is often toxic to gametes (Nijs et al. 2009 Fertil. Steril. 92, 527-535). In addition, gas molecules permeate through the plastic at a rate that depends on a variety of(More)
  • 1