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  • Nabil H. Chehab, Asra Malikzay, Elena S. Stavridi, Thanos D Halazonetis
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1999 (First Publication: 23 November 1999)
  • Stabilization of p53 in response to DNA damage is caused by its dissociation from Mdm2, a protein that targets p53 for degradation in the proteasome. Dissociation of p53 from Mdm2 could be caused byExpand
  • Elena S. Stavridi, Nabil H. Chehab, Asra Malikzay, Thanos D Halazonetis
  • Biology, Medicine
  • Cancer research
  • 2001 (First Publication: 1 October 2001)
  • Ionizing radiation (IR) induces an increase in the levels and activity of the p53 tumor suppressor protein. The increased activity is attributed to IR-induced posttranslational modifications, some ofExpand