Nabendu N. Saha

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The Indian freshwater air-breathing catfishes Heteropneustes fossilis and Clarias batrachus are hardy and capable of living in derelict water bodies and tolerating temporary water deprivation. Several studies have been made on their ureogenic adaptations, ureogenic metabolic machinery, and regulation under different physiological and environmental(More)
Two new glucuronide paclitaxel prodrugs have been synthesized. Linked to the 2'-OH of the drug by a carbonate function, they include a self-immolative spacer bearing an arylnitro or arylamino group between the drug and the glucuronic acid residue. Both prodrugs were well detoxified and easily cleaved in the presence of beta-D-glucuronidase with fast removal(More)