Na Yin

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Mechanistic target of rapamycin complex 1 (mTORC1) integrates diverse environmental signals to control cellular growth and organismal homeostasis. In response to nutrients, Rag GTPases recruit mTORC1 to the lysosome to be activated, but how Rags are regulated remains incompletely understood. Here, we show that Sestrins bind to the heterodimeric(More)
In this study we consider the single machine scheduling problems with sum-of-logarithm-processing-times based deterioration, i.e., the actual job processing time is a function of the sum of the logarithm of the processing times of the jobs already processed. We show that even with the introduction of the sum-of-logarithm-processing-times based deterioration(More)
Protein modification by ubiquitin (Ub) and ubiquitin-like proteins (Ubls) is among the most complex and heavily investigated mechanisms of posttranslational protein regulation in eukaryotes. Moreover, Ub plays diverse roles in the regulation of numerous biological pathways. In this study, a suppression-subtractive hybridization cDNA library has been(More)
To identify differential proteins induced by N-(2-chloro-4-pyridy)-N′-phenylurea or forchlorfenuron (CPPU), two-dimensional electrophoresis was used to study the variations in protein expression of wheat seedlings induced with CPPU. The expressed protein spots were identified by matrix-assisted laser desorption/ionization–time of flight mass spectrometry(More)
In this work, we investigated the effect of Sep15 gene knockdown on apoptosis in human lens epithelial (hLE) cells, trying to understand the relevance of Sep15 to cataract formation in the Sep15 knockout (KO) mice. The results showed that sole knockdown of Sep15 by RNA interference did not result in apoptosis; however, reduction of Sep15 expression(More)
—Slip and fall is a serious problem which affects the health and safety of people, and it has become a hot topic in the ergonomics and biomedicine fields in recent years. The causes of slip and fall accidents including external causes and internal causes. And it is the body response coordination ability under the condition of instability that is one of the(More)
Intrahepatic cholestasis of pregnancy (ICP) is associated with increased perinatal mortality and morbidity. Circulating cell-free fetal DNA has been a useful parameter for monitoring of pregnancy-associated diseases. The purpose of this study was to determine the concentrations of hypermethylated RAS-association domain family 1, isoform A (RASSF1A) gene(More)