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A Dynamic Programming Model for Text Segmentation Based on Min-Max Similarity

• Na Ye, Jingbo Zhu, Yan Zheng, Matthew Y. Ma, Huizhen Wang, Bin Zhang
• AIRS
• 2008

ent-Kaurane-based regio- and stereoselective inverse electron demand hetero-Diels-Alder reactions: synthesis of dihydropyran-fused diterpenoids.

• Chunyong Ding, Lili Wang, +7 authors Jia Zhou
• Organic & biomolecular chemistry
• 2014

A mild and concise approach for the construction of a 3,4-dihydro-2H-pyran ring integrated into the A-ring of the natural product oridonin using an optimized inverse electron demand… (More)

Biochemical and Pharmacological Characterizations of ESI-09 Based EPAC Inhibitors: Defining the ESI-09 “Therapeutic Window”

• Yingmin Zhu, Haijun Chen, +5 authors Xiaodong Cheng
• Scientific reports
• 2015

The cAMP signaling cascade is one of the most frequently targeted pathways for the development of pharmaceutics. A plethora of recent genetic and pharmacological studies suggest that exchange… (More)

Synthesis of dihydrofuroaporphine derivatives: identification of a potent and selective serotonin 5-HT 1A receptor agonist.

• Zhili Liu, Hai Zhang, +6 authors Ao Zhang
• Journal of medicinal chemistry
• 2010

A series of new aporphine analogues were synthesized and pharmacologically evaluated. 11-Allyloxy-(17), 11-propargyloxy-(20), and dihydrofuro-(19) aporphines displayed the highest affinity at the… (More)

Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis.

• Chunyong Ding, Yusong Zhang, +8 authors Jia Zhou
• Journal of medicinal chemistry
• 2013

Oridonin (1) has attracted considerable attention in recent years because of its unique and safe anticancer pharmacological profile. Nevertheless, it exhibits moderate to poor effects against highly… (More)

Identification of N-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate as a new anti-Parkinson's agent possessing a dopamine D2 and serotonin 5-HT1A dual-agonist profile.

• Hai Zhang, Na Ye, +6 authors Ao Zhang
• Journal of medicinal chemistry
• 2011

A series of new aporphine analogues (aporlogues) were synthesized bearing a C-, N-, or O-linkage at the C11 position. Lipoic ester (-)-15 was identified as a full agonist at the dopamine D(2) and… (More)

Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).

• Haijun Chen, C. Wild, Xiaobin Zhou, Na Ye, Xiaodong Cheng, Jia Zhou
• Journal of medicinal chemistry
• 2014

3',5'-Cyclic adenosine monophosphate (cAMP) is a pivotal second messenger that regulates numerous biological processes under physiological and pathological conditions, including cancer, diabetes,… (More)

Automatic Web Query Classification Using Large Unlabeled Web Pages

• Jingbo Yu, Na Ye
• 2008 The Ninth International Conference on Web…
• 2008

In this paper, a novel and simple method is employed to automatically construct domain knowledge base for query classification from large-scale Web pages. Besides, using context as the feature of… (More)

A naturally occurring amino acid substitution in the voltage-dependent sodium channel selectivity filter affects channel gating

• Mingming Wu, Na Ye, Biswa Sengupta, Harold H Zakon
• Journal of Comparative Physiology A
• 2013

The pore of sodium channels contains a selectivity filter made of 4 amino acids, D/E/K/A. In voltage sensitive sodium channel (Nav) channels from jellyfish to human the fourth amino acid is Ala. This… (More)

Improvement of the dotplotting method for linear text segmentation

• Na Ye, Jingbo Zhu, Haitao Luo, Huizhen Wang, Bin Zhang
• 2005 International Conference on Natural Language…
• 2005

The dotplotting method, employed by Reynar (1994), is a state-of-the-art algorithm for automatic linear text segmentation. However, several problems are found in its measure for assessing density… (More)

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