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Beta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in nonmuscle cells
- A. Belkin, N. Zhidkova, +6 authors K. Burridge
- Medicine, Biology
- The Journal of cell biology
- 1 January 1996
The cytoplasmic domains of integrins provide attachment of these extracellular matrix receptors to the cytoskeleton and play a critical role in integrin-mediated signal transduction. In this report… Expand
Autosomal dominant and recessive osteochondrodysplasias associated with the COL11A2 locus
Identifying mutations that cause specific osteochondrodysplasias will provide novel insights into the function of genes that are essential for skeletal morphogenesis. We report here that an autosomal… Expand
Integrin Displaces the [ 31 A Isoform in Striated Muscles : Localization at Junctional Structures and Signaling Potential in Nonmuscle Cells
The cytoplasmic domains of integrins provide attachment of these extracellular matrix receptors to the cytoskeleton and play a critical role in integrinmediated signal transduction. In this report we… Expand
Alternative mRNA processing occurs in the variable region of the pro-alpha 1(XI) and pro-alpha 2(XI) collagen chains.
An analysis was performed of differential splicing of primary transcripts in the noncollagenous variable region located in the amino terminus of the pro-alpha 1(XI) and pro-alpha 2(XI) collagen… Expand
Novel isoform of beta 1 integrin expressed in skeletal and cardiac muscle.
We describe a novel isoform of the beta 1 integrin subunit called beta 1D, which contains a unique cytoplasmic domain, and is expressed specifically in skeletal and cardiac muscle. The beta 1D… Expand
Alternative mRNA Processing Occurs in the Variable Region of the Pro-1(XI) and Pro-2(XI) Collagen Chains (*)
An analysis was performed of differential splicing of primary transcripts in the noncollagenous variable region located in the amino terminus of the pro-α1(XI) and pro-α2(XI) collagen chains. The… Expand
Meta‐vinculin distribution in adult human tissues and cultured cells
Meta‐vinculin distribution in adult human tissue was studied by immunoblotting technique. Meta‐vinculin was found in smooth (aorta wall and myometrium) and cardiac muscle, rather than in skeletal… Expand
Localization of talin in skeletal and cardiac muscles
Antibodies to talin and vinculin were used for localization of these proteins in skeletal and cardiac muscles by the indirect immunofluorescence method. We have found that talin is localized in… Expand
Organization of the human gene encoding the cytoskeletal protein vinculin and the sequence of the vinculin promoter.
- E. P. Moiseyeva, P. A. Weller, +5 authors D. Critchley
- Biology, Medicine
- The Journal of biological chemistry
- 25 February 1993
The human vinculin gene contains 22 exons ranging in size from 71 base pairs (bp) to 303 bp (average 155 bp) with the exception of exon 22 which contains 144 bp of coding sequence and 1848 bp of… Expand
Complete sequence of human vinculin and assignment of the gene to chromosome 10.
- P. A. Weller, E. P. Ogryzko, +6 authors D. Critchley
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 1 August 1990
We have determined the complete sequence of human vinculin, a cytoskeletal protein associated with cell-cell and cell-matrix junctions. Comparison of human and chicken embryo vinculin sequences shows… Expand