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Concurrent overproduction of synapses in diverse regions of the primate cerebral cortex.
Synapses develop concurrently and at identical rates in different layers of the visual, somatosensory, motor, and prefrontal areas of the primate cerebral cortex. This isochronic course ofExpand
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Contributions of cortical subventricular zone to the development of the human cerebral cortex
The cortical subventricular zone (SVZ), a proliferative compartment in the forebrain, has a uniquely important role during the second half of intrauterine development in human. This is best observedExpand
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Development of Layer I Neurons in the Primate Cerebral Cortex
Layer I, which plays an important role in the development of the cerebral cortex, expands in size and diversity in primates. We found that, unlike in rodents, in the macaque monkey, neurons of thisExpand
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Interneurons in the developing human neocortex
Cortical interneurons play a crucial role in the functioning of cortical microcircuitry as they provide inhibitory input to projection (pyramidal) neurons. Despite their involvement in variousExpand
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Oligodendrocyte Development and the Onset of Myelination in the Human Fetal Brain
Oligodendrocytes are cells that myelinate axons, providing saltatory conduction of action potentials and proper function of the central nervous system. Myelination begins prenatally in the human, andExpand
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Olig Transcription Factors Are Expressed in Oligodendrocyte and Neuronal Cells in Human Fetal CNS
The transcription factors Olig1 and Olig2 are closely associated with the development of oligodendrocyte (OL) lineage in the vertebrate nervous system, but little is known about their role in theExpand
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Emerging complexity of layer I in human cerebral cortex.
In this study we examine possible origins and migratory routes of human cortical neurons, with special emphasis on the preplate and layer I. In embryonic stages, two main cell types, Cajal-RetziusExpand
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Specific characteristic of radial glia in the human fetal telencephalon
Phenotypic characteristics of cells in the developing human telencephalic wall were analyzed using electron microscopy and immunocytochemistry with various glial and neuronal cell markers. TheExpand
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Is Pax6 critical for neurogenesis in the human fetal brain?
Transcription factor Pax6 plays an important role in fate determination of neural progenitor cells in animal models, yet, its distribution and role in the human developing brain have not beenExpand
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Changes in synaptic density in motor cortex of rhesus monkey during fetal and postnatal life.
The density and proportion of synaptic contacts in the primate motor cortex (Brodmann area 4) were determined in 21 rhesus monkeys ranging in age from embryonic day 41 (E41) to 20 years. Two to 4Expand
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