Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5‐fluorouracil), and high dose radiation +…
One‐hundred‐ninety‐four eligible and evaluable patients with histologically confirmed locally unresectable adenocarcinoma of the pancreas were randomly assigned to therapy with high‐dose (6000 rads)…
Gastric acid barrier to ingested microorganisms in man: studies in vivo and in vitro
The `gastric bactericidal barrier' is primarily pH-hydrochloric acid dependent, with other constituents of gastric juice contributing little, if any, detectable effect on the destruction of microorganisms.
Factors influencing survival in patients with hepatic metastases from adenocarcinoma of the colon or rectum
- R. Goslin, G. Steele, N. Zamcheck, R. Mayer, J. Macintyre
- MedicineDiseases of the Colon & Rectum
- 1 November 1982
It is suggested that future therapeutic trials, using survival as a measure of response of patients with liver metastases from colorectal cancer, must be prospectively controlled before selection factors can be differentiated from significant therapy effect.
Factors controlling the circulating CEA levels in pancreatic cancer: Some clinical correlations
Some of the factors that influence plasma CEA levels in patients with pancreatic cancer are summarized and the use of serial CEA determinations reflects these several factors, providing opportunities for earlier diagnosis, evidence of curative resectability, detection of recurrence and metastatic spread.
Occurrence of gastric cancer among patients with pernicious anemia at the Boston City Hospital.
Differences in the sampling methods, the relatively small number of patients with pernicious anemia available at any one clinic and the differing criteria utilized for the diagnosis of pernitic anemia contribute to the disparity among reported rates.
Correlation of Plasma CEA and CEA tissue staining in poorly differentiated colorectal cancer.
Immunologic diagnosis and prognosis of human digestive-tract cancer: carcinoembryonic antigens.
A large number of tumors form antigens thought to be "specific" — i.e., not present in nonmalignant tissues or present in lesser or inconsequential amounts, but detected in minute amounts by immunochemical methods.
Clinical Giardiasis and Intestinal Malabsorption
The effect of sodium butyrate and retinoic acid on growth and CEA production in a series of human colorectal tumor cell lines representing different states of differentiation.
The effect of sodium butyrate and retinoic acid added singly or in combination on substrate-dependent growth, colonization efficiency in soft agar, and carcino-embryonic antigen (CEA) production in…
Influence of gastric acidity on bacterial and parasitic enteric infections. A perspective.
A large number of patients with reduced gastric acid secretion were thought to be especially susceptible to bacterial enteric infections, but the mechanism behind this belief is still unclear.