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Identification of 33 polymorphisms in the adipocyte‐derived leucine aminopeptidase (ALAP) gene and possible association with hypertension
TLDR
Findings support involvement of ALAP in the regulation of blood pressure by confirming association between the Lys528Arg polymorphism and essential hypertension. Expand
Linkage and association of febrile seizures to the IMPA2 gene on human chromosome 18
TLDR
A novel locus on chromosome 18p11.2 for febrile seizures (FSs) is found, likely to be an FS susceptibility gene, which encodes myo-inositol monophosphatase (IMPase) 2. Expand
Frequent occurrence of hypoalphalipoproteinemia due to mutant apolipoprotein A-I gene in the population: a population-based survey.
TLDR
The frequency of hypoalphalipoproteinemia due to a mutant apolipoprotein A-I gene was estimated at 6% in the subjects with low HDL cholesterol levels and 0.3% (95% CI: 0.1-0.8%) in the Japanese population, which suggests that familial hypo Ralphalipopritesinema due to apo A- I gene mutations is relatively common. Expand
Failure to find evidence for association between voltage-gated sodium channel gene SCN2A variants and febrile seizures in humans
TLDR
This study failed to provide evidence supporting a causal relation between the SCN2A mutation/polymorphism and FS or FS associated with afebrile seizures including GEFS+ in the Japanese population. Expand
Mutation analysis of the calpastatin gene (CAST) in patients with Alzheimer's disease
TLDR
Comparisons between 101 patients and 90 controls revealed no significant association between CAST polymorphisms and risk for AD, indicating that genomic variations of CAST are not likely to be substantially involved in the etiology of AD. Expand