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Ovarian tumors in a cohort of infertile women.
TLDR
Prolonged use of clomiphene may increase the risk of a borderline or invasive ovarian tumor in women evaluated for infertility between 1974 and 1985.
Increased risk of hip fracture among patients with end-stage renal disease.
TLDR
The overall risk of hip fracture among Caucasian patients with ESRD is considerably higher than in the general population, independent of age and gender.
Temporal trends in the prevalence of diabetic kidney disease in the United States.
TLDR
Prevalence of DKD in the United States increased from 1988 to 2008 in proportion to the prevalence of diabetes, and was stable despite increased use of glucose-lowering medications and renin-angiotensin-aldosterone system inhibitors among persons with diabetes.
A case-control study of screening sigmoidoscopy and mortality from colorectal cancer.
TLDR
Screening by sigmoidoscopy can reduce mortality from cancer of the rectum and distal colon and a screening once every 10 years may be nearly as efficacious as more frequent screening.
Relationship between long durations and different regimens of hormone therapy and risk of breast cancer.
TLDR
It is suggested that use of CHRT is associated with an increased risk of breast cancer, particularly invasive lobular tumors, whether the progestin component was taken in a sequential or in a continuous manner.
Risk of hip fracture among dialysis and renal transplant recipients.
TLDR
The high risk of hip fracture among dialysis patients is exceeded by that among renal transplant patients during the first 1 to 3 years after transplantation, and among transplant recipients, risk of fracture was relatively higher in persons with a prolonged period of dialysis before transplantation.
Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis.
TLDR
Low-dose diuretics are the most effective first-line treatment for preventing the occurrence of cardiovascular disease morbidity and mortality and future trials should use low-doseDiuretics as the standard for clinically useful comparisons.
Evaluation of human papillomavirus testing in primary screening for cervical abnormalities: comparison of sensitivity, specificity, and frequency of referral.
TLDR
Testing for HPV has higher sensitivity but lower specificity than thin-layer Pap screening, and screening for HPV DNA may be a reasonable alternative to cytology-based screening of reproductive-age women in some settings.
Sharing of drug preparation equipment as a risk factor for hepatitis C.
TLDR
Among injection drug users who do not share syringes, an important proportion of HCV infections may be attributed to cooker/cotton sharing, and this study investigated the sharing of drug preparation equipment as a possible route of hepatitis C virus transmission.
The incidence of primary cardiac arrest during vigorous exercise.
TLDR
Although the risk of primary cardiac arrest is transiently increased during vigorous exercise, habitual vigorous exercise is associated with an overall decreased risk ofPrimary cardiac arrest.
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