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  • Morgane Gourlaouen, Jonathan C. Welti, Naveen S. Vasudev, Andrew R. Reynolds
  • Medicine, Biology
  • The Journal of Biological Chemistry
  • 2013 (First Publication: 22 January 2013)
  • Background: Growth factor receptors in endothelial cells are an important therapeutic target for anti-angiogenic therapy. Results: Inhibitors of endocytosis suppress ERK1/2 activation downstream ofExpand
  • Victoria Louise Bridgeman, Peter B. Vermeulen, +19 authors Andrew R. Reynolds
  • Medicine
  • The Journal of pathology
  • 2017 (First Publication: 29 December 2016)
  • Abstract Anti‐angiogenic therapies have shown limited efficacy in the clinical management of metastatic disease, including lung metastases. Moreover, the mechanisms via which tumours resistExpand
  • Peter J. Gad Jan O. Joshua M. Jennifer L. Lincoln D. Mar Campbell Getz Korbel Stuart Jennings Stein Perry N, P. J. Campbell, +1,338 authors J. Zhang
  • Biology, Medicine
  • Nature
  • 2020 (First Publication: 1 February 2020)
  • Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1–3. Here we report the integrativeExpand