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Emergence of resistance to biocides during differentiation of Acanthamoeba castellanii.
A synchronous encystment method was used to study the order of development of resistance of Acanthamoeba castellanii to a range of biocides. The emerging resistance during encystation to short-termExpand
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Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern pathogens. The same organism that lives as a commensal and is transmitted in both health-care and communityExpand
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B1 and TRPV-1 Receptor Genes and Their Relationship to Hyperalgesia Following Spinal Cord Injury
Study Design. Laboratory investigation of pain behavior following spinal cord injury. Objective. To explore changes in the spinal cord expression of nociceptive genes following spinal cord injuryExpand
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Antihyperalgesic effects of vanilloid-1 and bradykinin-1 receptor antagonists following spinal cord injury in rats.
OBJECT The authors previously discovered that genes for the bradykinin-1 (B1) receptor and the transient receptor potential vanilloid subtype 1 (TRPV1) were overexpressed in animals exhibitingExpand
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Encystation in Acanthamoeba castellanii: Development of Biocide Resistance1
Abstract Since the early 1960s, axenic culture and the development of procedures for the induction of encystation have made Acanthamoeba spp. superb experimental systems for studies of cell biologyExpand
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WHIM syndrome caused by a single amino acid substitution in the carboxy-tail of chemokine receptor CXCR4.
WHIM syndrome is a rare, autosomal dominant, immunodeficiency disorder so-named because it is characterized by warts, hypogammaglobulinemia, infections, and myelokathexis (defective neutrophil egressExpand
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Use of Letermovir as Salvage Therapy for Drug-Resistant Cytomegalovirus Retinitis
  • N. Turner, Andrew Strand, +6 authors Cameron R Wolfe
  • Medicine, Biology
  • Antimicrobial Agents and Chemotherapy
  • 14 January 2019
Treatment options for drug-resistant cytomegalovirus (CMV) are limited. Letermovir is a novel antiviral recently approved for CMV prophylaxis following hematopoietic cell transplantation, but itsExpand
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Resistance, biguanide sorption and biguanide‐induced pentose leakage during encystment of Acanthamoeba castellanii
Aims:  This study investigates the effects of biguanides during encystment of Acanthamoeba castellanii.
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Microbial differentiation and changes in susceptibility to antimicrobial agents
Different types of microbes vary in their response to antibiotics and other antimicrobial agents (McDonnell and Russell 1999; Russell 1999). With antibiotics and other chemotherapeutic agents, theExpand
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Entamoeba invadens: the requirement for galactose ligands during encystment.
During periods of stress, trophozoites of Entamoeba invadens (strain IP-1) undergo a process of differentiation (encystment) that results in a dormant cyst with a chitin-containing cyst wall.Expand
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