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A Randomized Trial of Prenatal Versus Postnatal Repair of Myelomeningocele
Spina bifida is the most common of congenital central nervous system abnormalities that are compatible with life. The most frequent type of neural tube defect is myelomeningocele, in which the spinalExpand
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Fetal surgery for myelomeningocele and the incidence of shunt-dependent hydrocephalus.
CONTEXT Intrauterine closure of exposed spinal cord tissue prevents secondary neurologic injury in animals with a surgically created spinal defect; however, whether in utero repair ofExpand
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The Effect of Intrauterine Myelomeningocele Repair on the Incidence of Shunt-Dependent Hydrocephalus
Background: Intrauterine myelomeningocele repair (IUMR) was first successfully performed in 1997. Preliminary reports suggest that this procedure reduces the incidence of shunt-dependentExpand
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Endoscopic coverage of fetal myelomeningocele in utero.
OBJECTIVE Our goal was to evaluate the safety and efficacy of minimally invasive surgery for the coverage of myelomeningocele in utero. STUDY DESIGN Women in the mid-second trimester of a pregnancyExpand
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Intrauterine repair of spina bifida: preoperative predictors of shunt-dependent hydrocephalus.
OBJECTIVE The objective of this study was to determine which factors that are present at the time of intrauterine repair of spina bifida could predict the need for ventriculoperitoneal shunt forExpand
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Prenatal surgery for myelomeningocele and the need for cerebrospinal fluid shunt placement.
OBJECT The Management of Myelomeningocele Study (MOMS) was a multicenter randomized trial comparing the safety and efficacy of prenatal and postnatal closure of myelomeningocele. The trial wasExpand
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A randomized trial of prenatal versus postnatal repair of myelomeningocele.
BACKGROUND Prenatal repair of myelomeningocele, the most common form of spina bifida, may result in better neurologic function than repair deferred until after delivery. We compared outcomes of inExpand
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In utero Repair of Myelomeningocele: A Comparison of Endoscopy and Hysterotomy
Objective: To compare endoscopic coverage of myelomeningocele with a maternal split-thickness skin graft in utero to definitive neurosurgical closure through a hysterotomy. Methods: Four fetuses withExpand
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Intrauterine repair of spina bifida.
Introduction In the current generation, 2 screening tests for neural tube defects are widely used. Combining the use of maternal serum alpha-fetoprotein screening with second-trimester ultrasoundExpand
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A Randomized Trial of Prenatal Versus Postnatal Repair of Myelomeningocele
ABSTRACTMyelomeningocele is one of the most common birth defects, characterized by a defect in the bony spine and resultant extrusion of the spinal cord into a sac filled with cerebrospinal fluid. ItExpand
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