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Low glomerular density with glomerulomegaly in obesity-related glomerulopathy.
BACKGROUND AND OBJECTIVES Obesity-related glomerulopathy is a secondary form of glomerular disease that may occur in obese individuals. It is histologically characterized by marked glomerulomegalyExpand
Glomerular Density-Associated Changes in Clinicopathological Features of Minimal Change Nephrotic Syndrome in Adults
Background: Differences in nephron number and/or glomerular size between individuals, in relation to intrauterine growth retardation or low birth weight, have been suggested to affect the clinicalExpand
New insights on glomerular hyperfiltration: a Japanese autopsy study.
It has been suggested that low nephron number contributes to glomerular hypertension and hyperperfusion injury in progressive chronic kidney disease (CKD). The incidence of CKD in Japan is among theExpand
Diffuse tubulointerstitial nephritis accompanied by renal crystal formation in an HIV-infected patient undergoing highly active antiretroviral therapy.
This report presents a human immunodeficiency virus (HIV) patient that developed a slowly progressive renal impairment over years under highly active antiretroviral therapy (HAART). The renal biopsyExpand
Reduction of proteinuria by therapeutic intervention improves the renal outcome of elderly patients with IgA nephropathy
BackgroundThe number of elderly patients with IgA nephropathy (IgAN) is increasing in parallel with the increased longevity in the general population. However, information is limited regarding theExpand
Glomerular density in renal biopsy specimens predicts the long-term prognosis of IgA nephropathy.
BACKGROUND AND OBJECTIVES An early histopathologic predictor of the renal prognosis, before the occurrence of advanced glomerular sclerosis/interstitial fibrosis and/or apparent renal dysfunction,Expand
Low glomerular density is a risk factor for progression in idiopathic membranous nephropathy.
BACKGROUND The adverse histological features predicting a progressive loss of renal function in idiopathic membranous nephropathy (IMN), before the establishment of impaired renal function withExpand
Changes in the glomerular density and size in serial renal biopsies during the progression of IgA nephropathy.
BACKGROUND Although there have been many reports on clinicopathological studies of IgAN, information is limited regarding the long-term evolution of a renal histology by analysing samples obtainedExpand
The predictive value of attenuated proteinuria at 1 year after steroid therapy for renal survival in patients with IgA nephropathy
BackgroundThe relationship between the urinary protein excretion (UPE) initially achieved after steroid therapy and the long-term renal outcome of IgA nephropathy (IgAN) has not been clarified. WeExpand
The long-term antiproteinuric effect of eplerenone, a selective aldosterone blocker, in patients with non-diabetic chronic kidney disease
Introduction: There is still insufficient data concerning the clinical effects of eplerenone, a selective aldosterone blocker, in patients with non-diabetic chronic kidney disease (CKD). Methods:Expand
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