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CD99 monoclonal antibody induce homotypic adhesion of Jurkat cells through protein tyrosine kinase and protein kinase C-dependent pathway.
It is shown here that LFA-1/ICAM-1 independent cell adhesion pathways are activated via CD99, suggesting that CD99 can mediate beta2-integrin independent cellAdhesion that depends on activation of protein kinases and reorganization of the cytoskeleton. Expand
Inhibition of PHA-induced cell proliferation by polyclonal CD4 antibodies generated by DNA immunization.
It is found that the polyclonal CD4 antibodies strongly suppressed PHA induced cell proliferation and indicated the possibility of utilizing DNA immunization to producepolyclonal antibodies against cell surface molecule. Expand
Production of mouse anti-CD4 antibodies by DNA-based immunization.
DNA-based immunization is capable of raising antibodies to human leukocyte surface antigens in mice or other animals and may be useful for producing antibodies to other cell surface antIGens in dogs, cats, and other animals. Expand
Production of monoclonal antibody to CD4 antigen and development of reagent for CD4+ lymphocyte enumeration.
The results suggest that home made FITC labeled MT4 reagent is an acceptable alternative reagent for monitoring CD4+ lymphocytes in blood samples by flow cytometry. Expand