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ASSOCIATION OF LOC387715 A69S GENOTYPE WITH VISUAL PROGNOSIS AFTER PHOTODYNAMIC THERAPY FOR POLYPOIDAL CHOROIDAL VASCULOPATHY
There is a pharmacogenetic association between the LOC387715 A69S variant and the long-term results after photodynamic therapy in eyes with PCV. Expand
Association of LOC387715 A69S with vitreous hemorrhage in polypoidal choroidal vasculopathy.
- Yoichi Sakurada, T. Kubota, F. Mabuchi, M. Imasawa, N. Tanabe, H. Iijima
- American journal of ophthalmology
- 14 May 2008
The LOC387715 polymorphism is associated with PCV and clinical severity in the subgroups of PCV in the Japanese population. Expand
Role of complement factor H I62V and age-related maculopathy susceptibility 2 A69S variants in the clinical expression of polypoidal choroidal vasculopathy.
At-risk variants of ARMS2 A69S were associated with higher incidences of subretinal hemorrhage, serous PED, and hemorrhagic PED and were significantly associated with hemorrhagic or subpigment epithelium lesions of PCV, and with earlier onset and bilateral involvement. Expand
Comparison of initial treatment between 3-monthly intravitreal aflibercept monotherapy and combined photodynamic therapy with single intravitreal aflibercept for polypoidal choroidal vasculopathy
- Wataru Kikushima, Yoichi Sakurada, Atsushi Sugiyama, N. Tanabe, Atsuki Kume, H. Iijima
- Graefe's Archive for Clinical and Experimental…
- 1 February 2017
The combination of PDT with IAI as the initial treatment for PCV may be superior to IAI monotherapy in terms of disease-stabilizing efficacy, but with equivalent visual gain at 12 months. Expand
A remote operating slit lamp microscope system. Development and its utility in ophthalmologic examinations.
The remote slit lamp has a similar diagnostic ability, but required more examination time in comparison to the conventional slit lamp, and has the potential to be employed for tele-medicine purposes in the field of ophthalmology. Expand
Prevalence and Genetic Characteristics of Geographic Atrophy among Elderly Japanese with Age-Related Macular Degeneration
Patients with GA were significantly older, with a higher prevalence of reticular pseudodrusen, bilateral involvement of advanced AMD and T-allele frequency of ARMS2 A69S compared with those with typical AMD and PCV; although there were no differences in the genetic and clinical characteristics among patients with GA and RAP. Expand
GENETIC FACTORS ASSOCIATED WITH CHOROIDAL VASCULAR HYPERPERMEABILITY AND SUBFOVEAL CHOROIDAL THICKNESS IN POLYPOIDAL CHOROIDAL VASCULOPATHY
Subfoveal choroidal thickness and CVH in eyes with treatment-naive polypoidal choroid vasculopathy were associated with ARMS2 A69S (rs10490924) and CFH (rs1329428), which are reportedly associated with central serous chorioretinopathy. Expand
Clinical and genetic characteristics of pachydrusen in patients with exudative age-related macular degeneration
We investigated the clinical and genetic characteristics of patients with unilateral exudative age-related macular degeneration (AMD), including typical AMD, polypoidal choroidal vasculopathy, and… Expand
Incidence and risk factors of retreatment after three-monthly aflibercept therapy for exudative age-related macular degeneration
The incidence and risk factors of retreatment after 3-monthly intravitreal aflibercept injection for exudative AMD during the 12-month period were investigated and found that best-corrected visual acuity (BCVA) improved significantly at 12 months. Expand
Comparison of two-year outcomes after photodynamic therapy with ranibizumab or aflibercept for polypoidal choroidal vasculopathy
Although there were no significant differences in the retreatment rate between the two groups, PDT/ IVA may be superior to PDT/IVR in terms of visual improvement at 24 months. Expand