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Age-related changes in cholesterol and bile acid metabolism in rats.
Serum and liver lipid levels increased with age in both strains but the liver phospholipid level remained unchanged, and the proportion of serum alpha-lipoprotein increases and that of beta- and prebeta- lipoproteins slightly decreased. Expand
Changes in biliary and fecal bile acids in mice after treatments with diosgenin and beta-sitosterol.
Diosgenin and beta-sitosterol were administered to CRJ:CD-1 male mice for 15 days, in order to examine the changes in bile acid metabolism, and both phytosterols caused no statistically significant changes in body weight gain and cholesterol absorption. Expand
Cholesterol gallstones in alloxan-diabetic mice.
Cholesterol gallstones developed in alloxan-diabetic mice fed excess cholesterol, due to the hyperphagia and the enhancement of cholesterol absorption caused by increases in the synthesis and secretion of cholic acid. Expand
Altered bile acid metabolism in alloxan diabetic rats.
It was apparent that synthesis of cholic acid increased while that of chenodeoxycholic acid decreased and the total amount of bile acids synthesized did not change in the diabetic rats. Expand
Effects of castration and testosterone administration on serum lipoproteins and their apoproteins in male spontaneously hypertensive rat.
The results suggest that testosterone reduces VLDL catabolism which is related to changes of apolipoprotein composition, and that hypertensive rats are more sensitive to testosterone than control rats. Expand
Effect of vitamin C depletion on serum cholesterol and lipoprotein levels in ODS (od/od) rats unable to synthesize ascorbic acid.
It is suggested that vitamin C deficiency delays low density lipoprotein metabolism and produces hypercholesterolemia in male od/od rats. Expand
Altered bile acid metabolism related to atherosclerosis in alloxan diabetic rats.
Normal and alloxan diabetic rats were kept on a 0.25% cholesterol diet for 12 months and the changes in serum cholesterol levels, and fecal excretion of sterols and bile acids were examined toExpand
Compositions of very low density lipoprotein subfractions from patients with polydisperse low density lipoproteins.
The results suggest that polydisperse LDL might be originated from VLDL that differs in particle sizes, densities and compositions from ordinary V LDL. Expand
Effect of dietary cholesterol on cholesterol and bile acid metabolism in rats.
It is concluded that dietary cholesterol increases the formation and excretion of chenodeoxycholic acid, and also that of cholic acid but to a lesser extent, and is responsible for the diminution of tissue and blood cholesterol. Expand
Pulmonary alveolar proteinosis: analysis of pulmonary washings.
Bronchopulmonary washings from a patient with pulmonary alveolar proteinosis who underwent therapeutic pulmonary lavage suggested that the alveoli-filling material of the patient was not wholely derived from passive transudation of plasma constituents. Expand