N. Sugiyama

Publications35
h-index13
Citations815
Highly Influential Citations39
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Germline‐specific expression of the Oct‐4/green fluorescent protein (GFP) transgene in mice
The Pic‐1, Oct‐1,2, Unc‐86 (POU) transcription factor Oct‐4 is specifically expressed in the germ cell line, and a previous study has indicated that the expression of the lacZ gene inserted into an… Expand
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Proprotein-processing endoprotease furin controls the growth and differentiation of gastric surface mucous cells.
Gastric surface mucous cells originate from progenitor cells at the isthmus of the gastric gland, from where the cells migrate to the luminal surface. With migration they form secretory granules and… Expand
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Establishment of gastric surface mucous cell lines from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene.
We succeeded in establishing two gastric surface mucous cell lines (designated as GSM06 and GSM10), which produce periodic acid-Schiff (PAS)- and concanavalin A (Con A)-positive glycoproteins, from a… Expand
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Biological characterization of gastric surface mucous cell line GSM06 from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene.
We investigated the biological features of gastric surface mucous cell line GSM06, established from transgenic mice harboring the temperature-sensitive simian virus 40 large T-antigen gene. GSM06… Expand
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Establishment and characterization of a colonic epithelial cell line MCE301 from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene.
We produced an immortalized colonic epithelial cell line, MCE301, using fetal mice transgenic for the temperature-sensitive simian virus 40 large T-antigen gene. MCE301 cells showed epithelial-like… Expand
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Luminescence cross-reactions of Porichthys luciferin and theories on the origin of luciferin in some shallow-water fishes.
Abstract 1. 1. Porichthys luciferin gives an extensive series of luminescent cross-reactions with the luciferases of various other luminous organisms. 2. 2. The luminescence reaction of Porichthys is… Expand
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An auto-inducible vector conferring high glucocorticoid inducibility upon stable transformant cells.
A new gene expression system in mammalian cells was developed by using the glucocorticoid receptor (GR) as an inducible positive feedback factor. Mouse Ltk- cells were transfected with plasmids… Expand
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Luminescent Systems in Apogonid Fishes from the Philippines
Luminescence has been discovered in five apogonid fishes from the Philippine Islands. The luminescent organ systems, which are of two types, are morphologically different from the systems in the… Expand
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Growing process to carcinoma of linitis plastica type of the stomach from cancer development
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Crystal-line luciferin from live Cypridina.
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