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In vivo histology of the myelin g-ratio with magnetic resonance imaging
SCT: Spinal Cord Toolbox, an open-source software for processing spinal cord MRI data
Quantifying the local tissue volume and composition in individual brains with MRI
A quantitative neuroimaging method to estimate the macromolecular tissue volume (MTV), a fundamental measure of brain anatomy, and shows that MTV provides a sensitive measure of disease status in individual patients with multiple sclerosis.
A robust methodology for in vivo T1 mapping
- J. Barral, E. Gudmundson, N. Stikov, M. Etezadi-Amoli, P. Stoica, D. Nishimura
- Computer ScienceMagnetic resonance in medicine
- 1 October 2010
A robust methodology for in vivo T1 mapping is presented, which is as accurate and precise as the conventionally used Levenberg‐Marquardt algorithm but much faster, and which makes the use of the five‐parameter model viable.
Practical medical applications of quantitative MR relaxometry
- Hai‐Ling Margaret Cheng, N. Stikov, N. Ghugre, G. Wright
- BiologyJournal of magnetic resonance imaging : JMRI
- 1 October 2012
An overview of some promising clinical applications of quantitative relaxometry is provided, followed by a description of the methods and challenges of acquiring accurate and precise quantitative MR maps, and three case studies of quantitative relaxation applied to studying multiple sclerosis, liver iron, and acute myocardial infarction.
Bound pool fractions complement diffusion measures to describe white matter micro and macrostructure
On the accuracy of T1 mapping: Searching for common ground
- N. Stikov, M. Boudreau, I. Levesque, C. Tardif, J. Barral, G. B. Pike
- MedicineMagnetic resonance in medicine
- 1 February 2015
Values in literature vary greatly, with T1 in white matter ranging from 690 to 1100 ms at 3 Tesla, calling into question the accuracy of one of the most fundamental measurements in quantitative MRI.
Promise and pitfalls of g-ratio estimation with MRI
Histological Underpinnings of Grey Matter Changes in Fibromyalgia Investigated Using Multimodal Brain Imaging
It is found that voxel-based morphometry is an exploratory measure, demonstrating the need to investigate the histological origin of gray matter alterations for every distinct clinical entity, and advances the understanding of the neurobiology of chronic (widespread) pain.