Pathogenicity of Mycobacterium tuberculosis Is Expressed by Regulating Metabolic Thresholds of the Host Macrophage
- Parul Mehrotra, Shilpa V. Jamwal, Kanury Rao
- BiologyPLoS Pathogens
- 1 July 2014
Whereas the requirement for macrophage survival sensitized TB susceptibility to the glycemic status of the individual, mediation by pathogen ensured that the virulence properties of the infecting strain also contributed towards the resulting pathology.
Therapeutic targets of triple‐negative breast cancer: a review
- V. Jamdade, N. Sethi, N. Mundhe, Parveen Kumar, M. Lahkar, N. Sinha
- Biology, MedicineBritish Journal of Pharmacology
- 1 September 2015
This review presents recent information associated with different therapeutic options for the treatment of TNBC focusing on promising targets such as the Notch signalling, Wnt/β‐catenin and Hedgehog pathways, in addition to EGFR, PARP1, mTOR, TGF‐β and angiogenesis inhibitors.
Hydroxychloroquine and COVID-19
- N. Sinha, Galit Balayla
- Medicine, BiologyPostgraduate medical journal
- 15 April 2020
The history and mechanism of actions of hydroxychloroquine and chloroquine, and the potential use they can have on the current covid-19 pandemic.
Teratogenic effects in rabbits of simultaneous exposure to ochratoxin A and aflatoxin B1 with special reference to microscopic effects.
- P. Wangikar, P. Dwivedi, N. Sinha, A. Sharma, A. Telang
- MedicineToxicology
- 5 November 2005
Effects of aflatoxin B1 on embryo fetal development in rabbits.
- P. Wangikar, P. Dwivedi, N. Sinha, A. Sharma, A. Telang
- MedicineFood and Chemical Toxicology
- 1 April 2005
The Behavior of Water in Collagen and Hydroxyapatite Sites of Cortical Bone: Fracture, Mechanical Wear, and Load Bearing Studies.
- F. Gul-E-Noor, C. Singh, A. Papaioannou, N. Sinha, G. Boutis
- PhysicsThe journal of physical chemistry. C…
- 17 September 2015
Reports on the dynamics, diffusion, population, and exchange of water in cortical bone by NMR relaxation and diffusion methodologies suggest that load bearing occurs largely in the collagen rich environment and is reversible.
Nano-Hydroxyapatite Bone Substitute Functionalized with Bone Active Molecules for Enhanced Cranial Bone Regeneration.
- A. Teotia, D. Raina, Ashok Kumar
- Medicine, BiologyACS Applied Materials and Interfaces
- 20 February 2017
NC can be used as a carrier for bioactive molecules, and functionalization with rhBMP-2 and ZA in low doses enhances bone regeneration.
Prevalence of coronary artery disease, lower extremity peripheral arterial disease, and cerebrovascular disease in 110 men with an abdominal aortic aneurysm.
- R. Sukhija, W. Aronow, K. Yalamanchili, N. Sinha, S. Babu
- MedicineAmerican Journal of Cardiology
- 15 November 2004
Effect in rats of simultaneous prenatal exposure to ochratoxin A and aflatoxin B1. II. Histopathological features of teratological anomalies induced in fetuses.
- P. Wangikar, P. Dwivedi, A. Sharma, N. Sinha
- MedicineBirth defects research. Part B. Developmental and…
- 1 December 2004
The present study indicates that the occurrence of brain, kidney, and liver lesions in combination treatment was less than in either individual treatment suggesting antagonism of OA-induced teratogenic effects by AFB1.
Metabolic fingerprinting in breast cancer stages through 1H NMR spectroscopy‐based metabolomic analysis of plasma
- S. Suman, R. K. Sharma, Vijay Kumar, N. Sinha, Y. Shukla
- BiologyJournal of Pharmaceutical and Biomedical Analysis
- 1 October 2018
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