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The Influence of Parturition on the Level and Synthesis of Sulfated and Free Neurosteroids in Rats
TLDR
Findings indicate an increase, not reflected in the brain cortex, in serum DHEA levels, at the end of pregnancy with a partial decrease following delivery and speculate that changes in the level or ratio of sulfated and free neurosteroids may play a role in postpartum behavioral disorders due to their antagonistic GABAA modulatory effect. Expand
Improved survival of zygotes in superovulated rats following surgical or pharmacological block of ovarian steroid secretion
TLDR
Test the hypothesis that the preimplantation losses of zygotes in pregnant superovulated juvenile rats was due to an imbalance of ovarian hormones and found that a lower dose reduced the recovery to the level of untreated animals, while increasing it to 60 mg resulted in maternal mortality and morbidity, as well as in developmental retardation ofZygotes. Expand
Endothelin and sarafotoxin: influence on steroid-regulated motility of rat uterus.
TLDR
It is concluded that the influence of the SRTXs and ETs on uterine motility depends on the hormonal status of the animal. Expand
Fetal Survival in the Rat as Affected by Intrauterine Injection of Serum Containing Antiphospholipid Antibodies
TLDR
An experimental rat model is established, enabling to study the intrauterine effect of serum, containing antiphospholipid antibodies, in vivo, and to examine whether the detrimental effect of antiph phosphate-based antibodies on gestation is locally derived. Expand
Effect of normal rat serum injected into the uterus on fetal survival in the rat
TLDR
The rat can provide a suitable animal model for further studies and has found an effect of normal rat serum on fetal resorption rate and fetal viability, according to the consistency of this effect. Expand
Human Decidua‐associated Protein 200 Neutralizes the Detrimental Effect of Serum Containing Antiphospholipid Antibodies on Fetal Survival in the Rat
TLDR
Whether the detrimental effect of serum containing antiphospholipid antibodies on rat pregnancy outcome can be neutralized by addition of human decidua‐associated protein (hDP) 200, a kind of rheumatoid factor, extracted from decidual tissue is examined. Expand
ORIGINAL ARTICLE: Pathomorphologic and Immunohistochemical Study on the Devastation of Rat Embryos by Antiphospholipid Antibody Positive Serum
TLDR
The aim was to examine the morphologic changes, induced in early rat embryos by intra‐uterine exposure to the low‐molecular weight fraction of boiled human serum containing antiphospholipid antibodies (APLA) that had been obtained from women with antiph phospholipids syndrome (APS). Expand
Effect of intrauterine injection of casein on fetal survival in rat: a new pharmacological approach for contraception.
TLDR
The data suggest a new pharmacological approach for contraception, based on local intrauterine effect of alpha-casein in an experimental rat model, and the exact mechanism of action related to casein should be further studied. Expand
Immunoaffinity purification and quantitation of a rat protein similar to the human decidua-associated protein (hDP) 71
TLDR
The results demonstrate the oestrogen-dependent accumulation of rDP 71 in uterine lumen, and support the use of a rat as an experimental animal model to investigate the possible physiological role of this protein in the reproductive process. Expand
Anordiol produces pregnancy loss in the rat--via the embryo or via the uterus?
TLDR
The results indicate that the effects of anordiol administration are exerted via the embryo as well as the uterus, and the agent in terminating pregnancy was determined on Day 14 of pregnancy. Expand