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Flow thresholds for extracellular purine catabolite elevation in cat focal ischemia
Ischemic glutamate excitotoxicity may be counteracted by adenosine which appears extracellularly during ischemia as an intermediate purine catabolite and has the potential to modulate glutamate… Expand
Ischemia‐Induced Accumulation of Extracellular Amino Acids in Cerebral Cortex, White Matter, and Cerebrospinal Fluid
Abstract: In a global model of brain ischemia, accumulation of amino acids was studied in the extracellular space of the auditory cortex and the internal capsule using microdialysis, and in CSF of… Expand
Application of a rigid endoscope to the microsurgical management of 54 cerebral aneurysms: results in 48 patients.
OBJECT To enhance visual confirmation of regional anatomy, endoscopy was introduced during microsurgery for cerebral aneurysms. The risks and benefits are analyzed in the present study. METHODS The… Expand
Purine catabolites in cerebral interstitial fluid during progression of and recovery from ischemia.
The concentrations of purine catabolites in the cerebral interstitial fluid during progression of and recovery from ischemia were studied using brain microdialysis and high-performance liquid… Expand
[Extracellular purine catabolites and tissue nucleotides and purine catabolites during progression and recovery of ischemia].
During progression and recovery of ischemia, extracellular purine catabolites were measured and compared with purine catabolites and adenine nucleotide levels in the tissue. Ischemia was induced by… Expand
Ischemic Flow Threshold for Extracellular Glutamate Increase in Cat Cortex
- N. Shimada, R. Graf, G. Rosner, A. Wakayama, C. P. George, W. Heiss
- Chemistry, Medicine
- Journal of cerebral blood flow and metabolism…
- 1 October 1989
Extracellular glutamate (Glu), cerebral blood flow (CBF), and auditory-evoked potentials (AEPs) were measured concurrently using microdialysis and hydrogen clearance in the auditory cortex of… Expand
Differences in ischemia-induced accumulation of amino acids in the cat cortex.
It is well established that excitatory amino acid neurotransmitters are extensively liberated during ischemia and that they have neurotoxic properties contributing to neuronal injury. To study… Expand
Glioblastoma following radiotherapy in a patient with tuberous sclerosis.
- H. Matsumura, H. Takimoto, N. Shimada, M. Hirata, T. Ohnishi, T. Hayakawa
- Neurologia medico-chirurgica
- 1 May 1998
A 26-year-old male with tuberous sclerosis developed a glioblastoma in the right temporal lobe 8 years after surgical excision and irradiation of a subependymal giant cell astrocytoma. The… Expand
Effect of Adenosine Agonist (Propentofylline) on Rat Hippocampal Seizures Induced by Microdialysis with Potassium: Analysis Using Compressed EEG Power Spectrum Array
- K. Morimoto, Y. Nii, +4 authors Y. Hayashi
- Chemistry, Medicine
- The Japanese journal of psychiatry and neurology
- 1 June 1991
Alteration of ionic microenvironment has been proved to increase excitability in the brain and contribute to the onset of seizures.'6 In a series of our studies on experimental epilepsy, we have used… Expand
Temperature distribution produced by laser irradiation in a ventricle model. The use of airflow in neuroendoscopic surgery.
- M. Taniguchi, A. Kato, T. Yoshimine, N. Shimada, H. Takimoto, T. Hayakawa
- Materials Science, Medicine
- Neurological research
The changes in intraventricular temperature during potassium titanyl phosphate laser irradiation were investigated using a ventricle configuration model. The laser had an output of 3 to 20 watts in 1… Expand