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Kdo: a critical monosaccharide for bacteria viability.
Covering: 2000 to 2010 Kdo belongs to the 3-deoxysugar ‘family’ and is a critical monosaccharidic component of lipopolysaccharides (LPSs) in Gram-negative bacteria. The incorporation of Kdo intoExpand
DEVELOPMENT OF NOVEL MICROEMULSION BASED TOPICAL FORMULATION OF CLOBETASOL PROPIONATE AND SALICYLIC ACID FOR THE TREATMENT OF PSORIASIS
Clobetasol propionate a glucocorticoid receptor agonist is an effective anti-inflammatory, immunomodulatory and antiproliferative agent. Salicylic acid a lipophilic monohydroxybenzoic acid exhibitsExpand
Carbohydrate mimetics and scaffolds: sweet spots in medicinal chemistry.
Several glycoprocessing enzymes and glycoreceptors have been recognized as important targets for therapeutic intervention. This concept has inspired the development of important classes ofExpand
Discovery and design of carbohydrate-based therapeutics
Importance of the field: Till now, the importance of carbohydrates has been underscored, if compared with the two other major classes of biopolymers such as oligonucleotides and proteins. RecentExpand
Molecular dynamics investigation of cyclic natriuretic peptides: dynamic properties reflect peptide activity.
Natriuretic peptides (NPs) are a family of structurally related hormone/paracrine factors (ANP, BNP and CNP), which mediate a broad array of physiological effects by interacting with specificExpand
Carbohydrate scaffolds in chemical genetic studies.
Small molecules altering protein functions as inhibitors, agonists or antagonists, find application in systems biology enabling an analysis of the in vivo consequences of these alterations. In thisExpand
C‐type natriuretic peptide: Structural studies, fragment synthesis, and preliminary biological evaluation in human osteosarcoma cell lines
Natriuretic peptides (NP) are a family of structurally related but genetically distinct hormones/paracrine factors that regulate blood volume, blood pressure, ventricular hypertrophy, pulmonaryExpand
Aminolysis of Styrene Oxide Over Heterogeneous Acidic Catalysts
Silica alumina and silica zirconia mixed oxides are shown to be effective and regioselective catalysts for the aminolysis of styrene oxide under very mild experimental conditions, giving theExpand
New Concepts in Solid Acid Catalysis: Some Opportunities Offered by Dispersed Copper Oxide
Copper oxide supported on silica by the Chemisorption–Hydrolysis technique shows a moderate Lewis acidic character due to coordinative unsaturation of the finely dispersed supported metallic phase.Expand
SQAGs: A Stepping Stone in the Biotic World
Abstract Multi-targeting drug discovery research has been driven, medically, commercially and intellectually; this need has often been equated with the identification and exploitation of novelExpand
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