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- Publications
- Influence
Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours
- J. Galon, B. Mlecnik, +45 authors F. Pagès
- Medicine
- The Journal of pathology
- 10 December 2013
The American Joint Committee on Cancer/Union Internationale Contre le Cancer (AJCC/UICC) TNM staging system provides the most reliable guidelines for the routine prognostication and treatment of… Expand
Cancer classification using the Immunoscore: a worldwide task force
Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation of tissue samples obtained during surgical resection of the primary tumor. Traditional tumor staging… Expand
Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast…
- H. Asanuma, T. Torigoe, +5 authors N. Sato
- Biology, Medicine
- Cancer research
- 1 December 2005
Survivin, a member of the inhibitor of apoptosis protein family, is widely expressed in a variety of human cancer tissues. Survivin inhibits activation of caspases, and its overexpression can lead to… Expand
Prognostic significance of HLA class I expression in osteosarcoma defined by anti‐pan HLA class I monoclonal antibody, EMR8‐5
- T. Tsukahara, S. Kawaguchi, +10 authors N. Sato
- Medicine
- Cancer science
- 1 December 2006
With the goal of establishing efficacious peptide‐based immunotherapy for patients with bone and soft tissue sarcomas, we previously identified the cytotoxic T lymphocyte‐defined osteosarcoma… Expand
High expression of ALDH1 and SOX2 diffuse staining pattern of oral squamous cell carcinomas correlates to lymph node metastasis
- Yoshitaka Michifuri, Y. Hirohashi, +10 authors N. Sato
- Medicine
- Pathology international
- 1 October 2012
One of the major factors involved in the prognosis of oral squamous cell carcinoma (OSCC) patients is metastasis. Recent progress in cancer stem‐like cell/cancer‐initiating cell (CSC/CIC) research… Expand
Ovarian Cancer Stem Cells Are Enriched in Side Population and Aldehyde Dehydrogenase Bright Overlapping Population
- K. Yasuda, T. Torigoe, +9 authors N. Sato
- Medicine, Biology
- PloS one
- 13 August 2013
Cancer stem-like cells (CSCs)/cancer-initiaiting cells (CICs) are defined as a small population of cancer cells that have self-renewal capacity, differentiation potential and high tumor-initiating… Expand
Verotoxins induce apoptosis in human renal tubular epithelium derived cells.
- T. Taguchi, H. Uchida, +5 authors J. Fujimoto
- Biology, Medicine
- Kidney international
- 1 June 1998
Apoptosis mediated by verotoxins (VTs) has been identified in a renal carcinoma cell line, ACHN cells, which are an in vitro model of renal tubular epithelial cells. ACHN cells express the renal… Expand
IL-12 and IL-18 Are Increased and Stimulate IFN-γ Production in Sarcoid Lungs
- K. Shigehara, N. Shijubo, +8 authors N. Sato
- Medicine
- The Journal of Immunology
- 1 January 2001
Sarcoidosis is a systemic chronic granulomatous disease of unknown cause. Recent investigations revealed that the cytokine profile in inflamed lesions of sarcoidosis is Th1 dominant. To obtain better… Expand
Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells.
- S. Inoda, Y. Hirohashi, +13 authors N. Sato
- Biology, Medicine
- The American journal of pathology
- 1 April 2011
Cancer stem-like cells (CSCs) and tumor-initiating cells (TICs) are a small population of cancer cells that share three properties: tumor initiating ability, self-renewal, and differentiation. These… Expand
High-glucose-induced nuclear factor κB activation in vascular smooth muscle cells
- Y. Hattori, S. Hattori, N. Sato, K. Kasai
- Biology
- 1 April 2000
Objective: Vascular smooth muscle cell (VSMC) dysfunction plays a role in diabetic macrovasculopathy. This dysfunction may be caused or exacerbated by expression of many of genes potently activated… Expand