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Clinical and economic consequences of ventilator-associated pneumonia: A systematic review
Background:Ventilator-associated pneumonia (VAP) is the most common nosocomial infection in critically ill patients. The clinical and economic consequences of VAP are unclear, with a broad range of… Expand
The pathogenesis of ventilator-associated pneumonia: its relevance to developing effective strategies for prevention.
Ventilator-associated pneumonia (VAP) is the most common nosocomial infection in the intensive care unit and is associated with major morbidity and attributable mortality. Strategies to prevent VAP… Expand
Diagnosis of invasive aspergillosis using a galactomannan assay: a meta-analysis.
BACKGROUND A double-sandwich enzyme-linked immunosorbent galactomannan assay has been approved for surveillance for invasive aspergillosis in immunocompromised patients. We undertook a meta-analysis… Expand
Meta-Analysis: Methods for Diagnosing Intravascular DeviceRelated Bloodstream Infection
Context Several methods exist for diagnosing intravascular devicerelated bloodstream infection. Contribution This meta-analysis summarized data from 51 studies for 8 diagnostic methods. Paired… Expand
The risk of infection after nasal colonization with Staphylococcus aureus.
PURPOSE Nasal, axillary, or inguinal colonization with Staphylococcus aureus generally precedes invasive infection. Some studies have found that colonization with methicillin-resistant S. aureus… Expand
Voriconazole Therapeutic Drug Monitoring
ABSTRACT We report on 28 patients who underwent voriconazole monitoring because of disease progression or toxicity. A relationship (P < 0.025) between disease progression and drug concentration was… Expand
Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: a patient-level quantitative review of randomized trials.
- D. Andes, N. Safdar, +6 authors B. Kullberg
- Clinical infectious diseases : an official…
- 15 April 2012
BACKGROUND Invasive candidiasis (IC) is an important healthcare-related infection, with increasing incidence and a crude mortality exceeding 50%. Numerous treatment options are available yet… Expand
The Commonality of Risk Factors for Nosocomial Colonization and Infection with Antimicrobial-Resistant Staphylococcus aureus, Enterococcus, Gram-Negative Bacilli, Clostridium difficile, and Candida
Beginning in the late 20th century, we have witnessed a rapidly growing crisis in antibiotic resistance, especially among microorganisms that cause nosocomial infection (1-4). Most notable among… Expand
Risk of hemolytic uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 enteritis: a meta-analysis.
CONTEXT The use of antibiotics for treatment of Escherichia coli O157:H7 infection has become controversial since a recent small study found that it may increase the risk of hemolytic uremic syndrome… Expand
Current Trends in the Epidemiology and Outcomes of Clostridium difficile Infection.
Clostridium difficile is the most frequently identified cause of nosocomial diarrhea and has been associated with epidemics of diarrhea in hospitals and long-term care facilities. The continued… Expand