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A Pharmacokinetic Study of Intravenous CTLA4Ig, a Novel Immunosuppressive Agent, in Mice
Abstract Three skin-intact mice in each group received a single 0.07-, 0.29-, or 0.57-mg dose of CTLA4Ig intravenously (iv). Three skin-grafted mice received a single 0.29-mg dose iv and anotherExpand
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Effects of Age, Gender and Diurnal Variation on the Steady‐State Pharmacokinetics (PK) of BMS‐181101
Clinical Pharmacology & Therapeutics (1996) 59, 202–202; doi: 10.1038/sj.clpt.1996.306
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Single dose and multiple dose pharmacokinetics of 2′-fluoro-2′,3′-dideoxyadenosine and 2′-fluoro-2′,3′-dideoxyinosine, anti-HIV agents, in rats
SummaryA single and multiple dose pharmacokinetic (PK) study was conducted in rats following oral administration of 2′-fluoro-2′,3′-dideoxyadenosine (FddA) and 2′-fluoro-2′,3′-dideoxyinosine (FddI)Expand
Assessment of oral bioavailability and preclinical pharmacokinetics of DRF-6196, a novel oxazolidinone analogue, in comparison to linezolid®
SummaryThe aim of this study was to determine the bioavailability of a novel oxazolidinone, DRF-6196, in mice and rats followingintravenous (i.v) and oral dosing and to compare the pharmacokineticsExpand